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Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms.
Chen CY, Liu TZ, Chen CH, Wu CC, Cheng JT, Yiin SJ, Shih MK, Wu MJ, Chern CL. Chen CY, et al. Among authors: yiin sj. Food Chem Toxicol. 2007 Jul;45(7):1268-76. doi: 10.1016/j.fct.2007.01.008. Epub 2007 Jan 20. Food Chem Toxicol. 2007. PMID: 17321026
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