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Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response.
Johnson KC, Anderson KJ, Courtois ET, Gujar AD, Barthel FP, Varn FS, Luo D, Seignon M, Yi E, Kim H, Estecio MRH, Zhao D, Tang M, Navin NE, Maurya R, Ngan CY, Verburg N, de Witt Hamer PC, Bulsara K, Samuels ML, Das S, Robson P, Verhaak RGW. Johnson KC, et al. Among authors: yi e. Nat Genet. 2021 Oct;53(10):1456-1468. doi: 10.1038/s41588-021-00926-8. Epub 2021 Sep 30. Nat Genet. 2021. PMID: 34594038 Free PMC article.
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Kim H, Nguyen NP, Turner K, Wu S, Gujar AD, Luebeck J, Liu J, Deshpande V, Rajkumar U, Namburi S, Amin SB, Yi E, Menghi F, Schulte JH, Henssen AG, Chang HY, Beck CR, Mischel PS, Bafna V, Verhaak RGW. Kim H, et al. Among authors: yi e. Nat Genet. 2020 Sep;52(9):891-897. doi: 10.1038/s41588-020-0678-2. Epub 2020 Aug 17. Nat Genet. 2020. PMID: 32807987 Free PMC article.
Extrachromosomal DNA amplifications in cancer.
Yi E, Chamorro González R, Henssen AG, Verhaak RGW. Yi E, et al. Nat Rev Genet. 2022 Dec;23(12):760-771. doi: 10.1038/s41576-022-00521-5. Epub 2022 Aug 11. Nat Rev Genet. 2022. PMID: 35953594 Free PMC article. Review.
Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription.
Zhu Y, Gujar AD, Wong CH, Tjong H, Ngan CY, Gong L, Chen YA, Kim H, Liu J, Li M, Mil-Homens A, Maurya R, Kuhlberg C, Sun F, Yi E, deCarvalho AC, Ruan Y, Verhaak RGW, Wei CL. Zhu Y, et al. Among authors: yi e. Cancer Cell. 2021 May 10;39(5):694-707.e7. doi: 10.1016/j.ccell.2021.03.006. Epub 2021 Apr 8. Cancer Cell. 2021. PMID: 33836152 Free PMC article.
672 results