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Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Dacon C, Peng L, Lin TH, Tucker C, Lee CD, Cong Y, Wang L, Purser L, Cooper AJR, Williams JK, Pyo CW, Yuan M, Kosik I, Hu Z, Zhao M, Mohan D, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Murphy M, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Doranz BJ, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Mascola JR, Holbrook MR, Nemazee D, Wilson IA, Tan J. Dacon C, et al. Among authors: yewdell jw. Cell Host Microbe. 2023 Jun 14;31(6):1071-1072. doi: 10.1016/j.chom.2023.05.016. Cell Host Microbe. 2023. PMID: 37321165 Free PMC article. No abstract available.
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Dacon C, Peng L, Lin TH, Tucker C, Lee CD, Cong Y, Wang L, Purser L, Cooper AJR, Williams JK, Pyo CW, Yuan M, Kosik I, Hu Z, Zhao M, Mohan D, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Murphy M, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Doranz BJ, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Mascola JR, Holbrook MR, Nemazee D, Wilson IA, Tan J. Dacon C, et al. Among authors: yewdell jw. Cell Host Microbe. 2023 Jan 11;31(1):97-111.e12. doi: 10.1016/j.chom.2022.10.010. Epub 2022 Nov 7. Cell Host Microbe. 2023. PMID: 36347257 Free PMC article.
Enhanced virulence and waning vaccine-elicited antibodies account for breakthrough infections caused by SARS-CoV-2 delta and beyond.
Kwon HJ, Kosikova M, Tang W, Ortega-Rodriguez U, Radvak P, Xiang R, Mercer KE, Muskhelishvili L, Davis K, Ward JM, Kosik I, Holly J, Kang I, Yewdell JW, Plant EP, Chen WH, Shriver MC, Barnes RS, Pasetti MF, Zhou B, Wentworth DE, Xie H. Kwon HJ, et al. Among authors: yewdell jw. iScience. 2022 Dec 22;25(12):105507. doi: 10.1016/j.isci.2022.105507. Epub 2022 Nov 5. iScience. 2022. PMID: 36373096 Free PMC article.
Editorial response to Cosentino and Marino RE: detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination.
Stafford LS, Valcarce V, Henry M, Neu J, Parker L, Mueller M, Vicuna V, Gowen T, Cato E, Kosik I, Yewdell JW, Atkinson M, Cacho N, Li N, Larkin J 3rd. Stafford LS, et al. Among authors: yewdell jw. J Perinatol. 2023 Jun;43(6):828-829. doi: 10.1038/s41372-023-01660-1. Epub 2023 Apr 6. J Perinatol. 2023. PMID: 37024528 Free PMC article. No abstract available.
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut.
Das A, Martinez-Ruiz GU, Bouladoux N, Stacy A, Moraly J, Vega-Sendino M, Zhao Y, Lavaert M, Ding Y, Morales-Sanchez A, Harly C, Seedhom MO, Chari R, Awasthi P, Ikeuchi T, Wang Y, Zhu J, Moutsopoulos NM, Chen W, Yewdell JW, Shapiro VS, Ruiz S, Taylor N, Belkaid Y, Bhandoola A. Das A, et al. Among authors: yewdell jw. Immunity. 2024 Apr 18:S1074-7613(24)00206-1. doi: 10.1016/j.immuni.2024.04.001. Online ahead of print. Immunity. 2024. PMID: 38677292
C1q enables influenza hemagglutinin stem binding antibodies to block viral attachment and broadens the antibody escape repertoire.
Kosik I, Da Silva Santos J, Angel M, Hu Z, Holly J, Gibbs JS, Gill T, Kosikova M, Li T, Bakhache W, Dolan PT, Xie H, Andrews SF, Gillespie RA, Kanekiyo M, McDermott AB, Pierson TC, Yewdell JW. Kosik I, et al. Among authors: yewdell jw. Sci Immunol. 2024 Mar 22;9(93):eadj9534. doi: 10.1126/sciimmunol.adj9534. Epub 2024 Mar 22. Sci Immunol. 2024. PMID: 38517951
COVID-19 booster enhances IgG mediated viral neutralization by human milk in vitro.
Valcarce V, Stafford LS, Neu J, Parker L, Vicuna V, Cross T, D'Agati O, Diakite S, Haley A, Feigenbaum J, Al Mahmoud MY, Visvalingam A, Cacho N, Kosik I, Yewdell JW, Larkin J 3rd. Valcarce V, et al. Among authors: yewdell jw. Front Nutr. 2024 Feb 9;11:1289413. doi: 10.3389/fnut.2024.1289413. eCollection 2024. Front Nutr. 2024. PMID: 38406184 Free PMC article.
340 results