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ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis.
Farrawell NE, Bax M, McAlary L, McKenna J, Maksour S, Do-Ha D, Rayner SL, Blair IP, Chung RS, Yerbury JJ, Ooi L, Saunders DN. Farrawell NE, et al. Among authors: yerbury jj. Hum Mol Genet. 2023 Jul 4;32(14):2386-2398. doi: 10.1093/hmg/ddad063. Hum Mol Genet. 2023. PMID: 37220877 Free PMC article.
Extracellular Chaperones.
Dabbs RA, Wyatt AR, Yerbury JJ, Ecroyd H, Wilson MR. Dabbs RA, et al. Among authors: yerbury jj. Top Curr Chem. 2010 Aug 27. doi: 10.1007/128_2010_85. Online ahead of print. Top Curr Chem. 2010. PMID: 21516385
ANS binding reveals common features of cytotoxic amyloid species.
Bolognesi B, Kumita JR, Barros TP, Esbjorner EK, Luheshi LM, Crowther DC, Wilson MR, Dobson CM, Favrin G, Yerbury JJ. Bolognesi B, et al. Among authors: yerbury jj. ACS Chem Biol. 2010 Aug 20;5(8):735-40. doi: 10.1021/cb1001203. ACS Chem Biol. 2010. PMID: 20550130
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.
Zeineddine R, Pundavela JF, Corcoran L, Stewart EM, Do-Ha D, Bax M, Guillemin G, Vine KL, Hatters DM, Ecroyd H, Dobson CM, Turner BJ, Ooi L, Wilson MR, Cashman NR, Yerbury JJ. Zeineddine R, et al. Among authors: yerbury jj. Mol Neurodegener. 2015 Oct 31;10:57. doi: 10.1186/s13024-015-0053-4. Mol Neurodegener. 2015. PMID: 26520394 Free PMC article.
Walking the tightrope: proteostasis and neurodegenerative disease.
Yerbury JJ, Ooi L, Dillin A, Saunders DN, Hatters DM, Beart PM, Cashman NR, Wilson MR, Ecroyd H. Yerbury JJ, et al. J Neurochem. 2016 May;137(4):489-505. doi: 10.1111/jnc.13575. Epub 2016 Mar 8. J Neurochem. 2016. PMID: 26872075 Free article. Review.
CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.
Williams KL, Topp S, Yang S, Smith B, Fifita JA, Warraich ST, Zhang KY, Farrawell N, Vance C, Hu X, Chesi A, Leblond CS, Lee A, Rayner SL, Sundaramoorthy V, Dobson-Stone C, Molloy MP, van Blitterswijk M, Dickson DW, Petersen RC, Graff-Radford NR, Boeve BF, Murray ME, Pottier C, Don E, Winnick C, McCann EP, Hogan A, Daoud H, Levert A, Dion PA, Mitsui J, Ishiura H, Takahashi Y, Goto J, Kost J, Gellera C, Gkazi AS, Miller J, Stockton J, Brooks WS, Boundy K, Polak M, Muñoz-Blanco JL, Esteban-Pérez J, Rábano A, Hardiman O, Morrison KE, Ticozzi N, Silani V, de Belleroche J, Glass JD, Kwok JB, Guillemin GJ, Chung RS, Tsuji S, Brown RH Jr, García-Redondo A, Rademakers R, Landers JE, Gitler AD, Rouleau GA, Cole NJ, Yerbury JJ, Atkin JD, Shaw CE, Nicholson GA, Blair IP. Williams KL, et al. Among authors: yerbury jj. Nat Commun. 2016 Apr 15;7:11253. doi: 10.1038/ncomms11253. Nat Commun. 2016. PMID: 27080313 Free PMC article.
96 results