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SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.
Zeineddine R, Pundavela JF, Corcoran L, Stewart EM, Do-Ha D, Bax M, Guillemin G, Vine KL, Hatters DM, Ecroyd H, Dobson CM, Turner BJ, Ooi L, Wilson MR, Cashman NR, Yerbury JJ. Zeineddine R, et al. Among authors: yerbury jj. Mol Neurodegener. 2015 Oct 31;10:57. doi: 10.1186/s13024-015-0053-4. Mol Neurodegener. 2015. PMID: 26520394 Free PMC article.
SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS.
Farrawell NE, Lambert-Smith I, Mitchell K, McKenna J, McAlary L, Ciryam P, Vine KL, Saunders DN, Yerbury JJ. Farrawell NE, et al. Among authors: yerbury jj. J Cell Sci. 2018 Jun 12;131(11):jcs209122. doi: 10.1242/jcs.209122. J Cell Sci. 2018. PMID: 29748379 Free PMC article.
The prion-like nature of amyotrophic lateral sclerosis.
McAlary L, Yerbury JJ, Cashman NR. McAlary L, et al. Among authors: yerbury jj. Prog Mol Biol Transl Sci. 2020;175:261-296. doi: 10.1016/bs.pmbts.2020.07.002. Epub 2020 Sep 1. Prog Mol Biol Transl Sci. 2020. PMID: 32958236 Review.
Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS.
Farrawell NE, McAlary L, Lum JS, Chisholm CG, Warraich ST, Blair IP, Vine KL, Saunders DN, Yerbury JJ. Farrawell NE, et al. Among authors: yerbury jj. iScience. 2020 Oct 20;23(11):101700. doi: 10.1016/j.isci.2020.101700. eCollection 2020 Nov 20. iScience. 2020. PMID: 33196025 Free PMC article.
Proteostasis impairment and ALS.
Lambert-Smith IA, Saunders DN, Yerbury JJ. Lambert-Smith IA, et al. Among authors: yerbury jj. Prog Biophys Mol Biol. 2022 Oct;174:3-27. doi: 10.1016/j.pbiomolbio.2022.06.001. Epub 2022 Jun 15. Prog Biophys Mol Biol. 2022. PMID: 35716729 Review.
96 results