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NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models.
Sci Transl Med. 2021 Feb 3;13(579):eabb2181. doi: 10.1126/scitranslmed.abb2181.
Sci Transl Med. 2021.
PMID: 33536278
Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.
Kounde CS, Yeo HQ, Wang QY, Wan KF, Dong H, Karuna R, Dix I, Wagner T, Zou B, Simon O, Bonamy GMC, Yeung BKS, Yokokawa F.
Kounde CS, et al. Among authors: yeo hq.
Bioorg Med Chem Lett. 2017 Mar 15;27(6):1385-1389. doi: 10.1016/j.bmcl.2017.02.005. Epub 2017 Feb 4.
Bioorg Med Chem Lett. 2017.
PMID: 28216045
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Plant-derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications.
Lian MQ, Chng WH, Liang J, Yeo HQ, Lee CK, Belaid M, Tollemeto M, Wacker MG, Czarny B, Pastorin G.
Lian MQ, et al. Among authors: yeo hq.
J Extracell Vesicles. 2022 Dec;11(12):e12283. doi: 10.1002/jev2.12283.
J Extracell Vesicles. 2022.
PMID: 36519808
Free PMC article.
Review.
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