Yen HY - Search Results

1

Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization.

Bada Juarez JF, Judge PJ, Adam S, Axford D, Vinals J, Birch J, Kwan TOC, Hoi KK, Yen HY, Vial A, Milhiet PE, Robinson CV, Schapiro I, Moraes I, Watts A. Bada Juarez JF, et al. Among authors: yen hy. Nat Commun. 2021 Jan 27;12(1):629. doi: 10.1038/s41467-020-20596-0. Nat Commun. 2021. PMID: 33504778 Free PMC article.

2

Ligand binding to a G protein-coupled receptor captured in a mass spectrometer.

Yen HY, Hopper JTS, Liko I, Allison TM, Zhu Y, Wang D, Stegmann M, Mohammed S, Wu B, Robinson CV. Yen HY, et al. Sci Adv. 2017 Jun 16;3(6):e1701016. doi: 10.1126/sciadv.1701016. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28630934 Free PMC article.

3

Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces.

Ambrose S, Housden NG, Gupta K, Fan J, White P, Yen HY, Marcoux J, Kleanthous C, Hopper JTS, Robinson CV. Ambrose S, et al. Among authors: yen hy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14463-14468. doi: 10.1002/anie.201704849. Epub 2017 Sep 18. Angew Chem Int Ed Engl. 2017. PMID: 28884954 Free PMC article.

4

PtdIns(4,5)P₂ stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.

Yen HY, Hoi KK, Liko I, Hedger G, Horrell MR, Song W, Wu D, Heine P, Warne T, Lee Y, Carpenter B, Plückthun A, Tate CG, Sansom MSP, Robinson CV. Yen HY, et al. Nature. 2018 Jul;559(7714):423-427. doi: 10.1038/s41586-018-0325-6. Epub 2018 Jul 11. Nature. 2018. PMID: 29995853 Free PMC article.

5

State-dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo-Mimetic Membranes.

Song W, Yen HY, Robinson CV, Sansom MSP. Song W, et al. Among authors: yen hy. Structure. 2019 Feb 5;27(2):392-403.e3. doi: 10.1016/j.str.2018.10.024. Epub 2018 Dec 20. Structure. 2019. PMID: 30581046 Free PMC article.

6

Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors.

Urner LH, Liko I, Yen HY, Hoi KK, Bolla JR, Gault J, Almeida FG, Schweder MP, Shutin D, Ehrmann S, Haag R, Robinson CV, Pagel K. Urner LH, et al. Among authors: yen hy. Nat Commun. 2020 Jan 28;11(1):564. doi: 10.1038/s41467-020-14424-8. Nat Commun. 2020. PMID: 31992701 Free PMC article.

7

Combining native and 'omics' mass spectrometry to identify endogenous ligands bound to membrane proteins.

Gault J, Liko I, Landreh M, Shutin D, Bolla JR, Jefferies D, Agasid M, Yen HY, Ladds MJGW, Lane DP, Khalid S, Mullen C, Remes PM, Huguet R, McAlister G, Goodwin M, Viner R, Syka JEP, Robinson CV. Gault J, et al. Among authors: yen hy. Nat Methods. 2020 May;17(5):505-508. doi: 10.1038/s41592-020-0821-0. Epub 2020 May 4. Nat Methods. 2020. PMID: 32371966 Free PMC article.

8

Correlating Glycoforms of DC-SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry.

Yen HY, Liko I, Gault J, Wu D, Struwe WB, Robinson CV. Yen HY, et al. Angew Chem Int Ed Engl. 2020 Sep 1;59(36):15560-15564. doi: 10.1002/anie.202005727. Epub 2020 Jul 7. Angew Chem Int Ed Engl. 2020. PMID: 33462887 Free PMC article.

9

Structural insights into the lipid and ligand regulation of serotonin receptors.

Xu P, Huang S, Zhang H, Mao C, Zhou XE, Cheng X, Simon IA, Shen DD, Yen HY, Robinson CV, Harpsøe K, Svensson B, Guo J, Jiang H, Gloriam DE, Melcher K, Jiang Y, Zhang Y, Xu HE. Xu P, et al. Among authors: yen hy. Nature. 2021 Apr;592(7854):469-473. doi: 10.1038/s41586-021-03376-8. Epub 2021 Mar 24. Nature. 2021. PMID: 33762731

10

Detergent-free Lipodisq Nanoparticles Facilitate High-Resolution Mass Spectrometry of Folded Integral Membrane Proteins.

Hoi KK, Bada Juarez JF, Judge PJ, Yen HY, Wu D, Vinals J, Taylor GF, Watts A, Robinson CV. Hoi KK, et al. Among authors: yen hy. Nano Lett. 2021 Apr 14;21(7):2824-2831. doi: 10.1021/acs.nanolett.0c04911. Epub 2021 Mar 31. Nano Lett. 2021. PMID: 33787280 Free PMC article.

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