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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function.
Sugiura A, Andrejeva G, Voss K, Heintzman DR, Xu X, Madden MZ, Ye X, Beier KL, Chowdhury NU, Wolf MM, Young AC, Greenwood DL, Sewell AE, Shahi SK, Freedman SN, Cameron AM, Foerch P, Bourne T, Garcia-Canaveras JC, Karijolich J, Newcomb DC, Mangalam AK, Rabinowitz JD, Rathmell JC. Sugiura A, et al. Among authors: ye x. Immunity. 2022 Jan 11;55(1):65-81.e9. doi: 10.1016/j.immuni.2021.10.011. Epub 2021 Nov 11. Immunity. 2022. PMID: 34767747 Free PMC article.
CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation.
Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC. Beckermann KE, et al. Among authors: ye x. JCI Insight. 2020 Aug 20;5(16):e138729. doi: 10.1172/jci.insight.138729. JCI Insight. 2020. PMID: 32814710 Free PMC article.
Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.
Healey DCC, Cephus JY, Barone SM, Chowdhury NU, Dahunsi DO, Madden MZ, Ye X, Yu X, Olszewski K, Young K, Gerriets VA, Siska PJ, Dworski R, Hemler J, Locasale JW, Poyurovsky MV, Peebles RS Jr, Irish JM, Newcomb DC, Rathmell JC. Healey DCC, et al. Among authors: ye x. J Immunol. 2021 Mar 15;206(6):1127-1139. doi: 10.4049/jimmunol.2001029. Epub 2021 Feb 8. J Immunol. 2021. PMID: 33558372 Free PMC article.
Reovirus Low-Density Particles Package Cellular RNA.
Thoner TW Jr, Ye X, Karijolich J, Ogden KM. Thoner TW Jr, et al. Among authors: ye x. Viruses. 2021 Jun 8;13(6):1096. doi: 10.3390/v13061096. Viruses. 2021. PMID: 34201386 Free PMC article.
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