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Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction.
Liu X, Wang Y, Lu H, Li J, Yan X, Xiao M, Hao J, Alekseev A, Khong H, Chen T, Huang R, Wu J, Zhao Q, Wu Q, Xu S, Wang X, Jin W, Yu S, Wang Y, Wei L, Wang A, Zhong B, Ni L, Liu X, Nurieva R, Ye L, Tian Q, Bian XW, Dong C. Liu X, et al. Among authors: ye l. Nature. 2019 Mar;567(7749):525-529. doi: 10.1038/s41586-019-0979-8. Epub 2019 Feb 27. Nature. 2019. PMID: 30814730 Free PMC article.
Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection.
He R, Hou S, Liu C, Zhang A, Bai Q, Han M, Yang Y, Wei G, Shen T, Yang X, Xu L, Chen X, Hao Y, Wang P, Zhu C, Ou J, Liang H, Ni T, Zhang X, Zhou X, Deng K, Chen Y, Luo Y, Xu J, Qi H, Wu Y, Ye L. He R, et al. Among authors: ye l. Nature. 2016 Aug 2;537(7620):412-428. doi: 10.1038/nature19317. Nature. 2016. PMID: 27501245
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells.
Zhao L, He R, Long H, Guo B, Jia Q, Qin D, Liu SQ, Wang Z, Xiang T, Zhang J, Tan Y, Huang J, Chen J, Wang F, Xiao M, Gao J, Yang X, Zeng H, Wang X, Hu C, Alexander PB, Symonds ALJ, Yu J, Wan Y, Li QJ, Ye L, Zhu B. Zhao L, et al. Among authors: ye l. Nat Med. 2018 Oct;24(10):1536-1544. doi: 10.1038/s41591-018-0205-5. Epub 2018 Oct 8. Nat Med. 2018. PMID: 30297899 Free PMC article.
The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection.
Chen X, Cao G, Wu J, Wang X, Pan Z, Gao J, Tian Q, Xu L, Li Z, Hao Y, Huang Q, Wang P, Xiao M, Xie L, Tang S, Liu Z, Hu L, Tang J, He R, Wang L, Zhou X, Wu Y, Chen M, Sun B, Zhu B, Huang J, Ye L. Chen X, et al. Among authors: ye l. Cell Mol Immunol. 2020 Mar;17(3):247-260. doi: 10.1038/s41423-019-0219-z. Epub 2019 Mar 6. Cell Mol Immunol. 2020. PMID: 30842630 Free PMC article.
7,910 results