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New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy.
Uccello TP, Lesch ML, Kintzel SA, Gradzewicz LB, Lamrous L, Murphy SP, Fleming FJ, Mills BN, Murphy JD, Hughson A, Hannon G, Garrett-Larsen J, Qiu H, Drage MG, Ye J, Gavras NW, Keeley DC, Love TMT, Repasky EA, Lord EM, Linehan DC, Gerber SA. Uccello TP, et al. Among authors: ye j. Cell Death Dis. 2023 Jul 26;14(7):470. doi: 10.1038/s41419-023-05999-3. Cell Death Dis. 2023. PMID: 37495596 Free PMC article.
Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment.
Mills BN, Connolly KA, Ye J, Murphy JD, Uccello TP, Han BJ, Zhao T, Drage MG, Murthy A, Qiu H, Patel A, Figueroa NM, Johnston CJ, Prieto PA, Egilmez NK, Belt BA, Lord EM, Linehan DC, Gerber SA. Mills BN, et al. Among authors: ye j. Cell Rep. 2019 Oct 8;29(2):406-421.e5. doi: 10.1016/j.celrep.2019.08.095. Cell Rep. 2019. PMID: 31597100 Free PMC article.
Development of an Orthotopic Murine Model of Rectal Cancer in Conjunction With Targeted Short-Course Radiation Therapy.
Uccello TP, Kintzel SA, Mills BN, Murphy JD, Garrett-Larsen J, Battaglia NG, Rodriguez CJ, Drage MG, Ye J, Love TMT, Johnston CJ, Repasky EA, Qiu H, Linehan DC, Lord EM, Gerber SA. Uccello TP, et al. Among authors: ye j. Adv Radiat Oncol. 2021 Dec 9;7(2):100867. doi: 10.1016/j.adro.2021.100867. eCollection 2022 Mar-Apr. Adv Radiat Oncol. 2021. PMID: 35036637 Free PMC article.
Radiation Therapy Exacerbates Tumor-Promoting Innervation and Nerve Signaling in Rectal Cancer.
Uccello TP, Lesch ML, Ullman NA, Kintzel SA, Gradzewicz LB, Velagaleti T, Fleming FJ, Mills BN, Murphy JD, Garrett-Larsen J, Qiu H, Drage MG, Ye J, Gavras NW, Johnston CJ, Love TMT, Repasky EA, Linehan DC, Lord EM, Gerber SA. Uccello TP, et al. Among authors: ye j. Int J Radiat Oncol Biol Phys. 2023 Mar 1;115(3):733-745. doi: 10.1016/j.ijrobp.2022.09.080. Epub 2022 Oct 4. Int J Radiat Oncol Biol Phys. 2023. PMID: 36202180 Free PMC article.
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