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Spermine promotes pulmonary vascular remodelling and its synthase is a therapeutic target for pulmonary arterial hypertension.
He YY, Yan Y, Jiang X, Zhao JH, Wang Z, Wu T, Wang Y, Guo SS, Ye J, Lian TY, Xu XQ, Zhang JL, Sun K, Peng FH, Zhou YP, Mao YM, Zhang X, Chen JW, Zhang SY, Jing ZC. He YY, et al. Among authors: ye j. Eur Respir J. 2020 Nov 5;56(5):2000522. doi: 10.1183/13993003.00522-2020. Print 2020 Nov. Eur Respir J. 2020. PMID: 32513782 Free article.
Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension.
Wang XJ, Xu XQ, Sun K, Liu KQ, Li SQ, Jiang X, Zhao QH, Wang L, Peng FH, Ye J, Wu Y, Jiang R, Zhang J, Huang W, Wei WB, Yan Y, Li JH, Liu QQ, Li S, Wang Y, Zhang SY, Zhang X, Jing ZC. Wang XJ, et al. Among authors: ye j. JAMA Cardiol. 2020 Jun 1;5(6):677-684. doi: 10.1001/jamacardio.2020.0479. JAMA Cardiol. 2020. PMID: 32236489 Free PMC article.
Germline BMP9 mutation causes idiopathic pulmonary arterial hypertension.
Wang XJ, Lian TY, Jiang X, Liu SF, Li SQ, Jiang R, Wu WH, Ye J, Cheng CY, Du Y, Xu XQ, Wu Y, Peng FH, Sun K, Mao YM, Yu H, Liang C, Shyy JY, Zhang SY, Zhang X, Jing ZC. Wang XJ, et al. Among authors: ye j. Eur Respir J. 2019 Mar 14;53(3):1801609. doi: 10.1183/13993003.01609-2018. Print 2019 Mar. Eur Respir J. 2019. PMID: 30578397 Free article.
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