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Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy.
Boyle AJ, Shih H, Hwang J, Ye J, Lee B, Zhang Y, Kwon D, Jun K, Zheng D, Sievers R, Angeli F, Yeghiazarians Y, Lee R. Boyle AJ, et al. Among authors: ye j. Exp Gerontol. 2011 Jul;46(7):549-59. doi: 10.1016/j.exger.2011.02.010. Epub 2011 Mar 3. Exp Gerontol. 2011. PMID: 21377520 Free PMC article.
The effects of aging on apoptosis following myocardial infarction.
Boyle AJ, Hwang J, Ye J, Shih H, Jun K, Zhang Y, Fang Q, Sievers R, Yeghiazarians Y, Lee RJ. Boyle AJ, et al. Among authors: ye j. Cardiovasc Ther. 2013 Dec;31(6):e102-10. doi: 10.1111/1755-5922.12043. Cardiovasc Ther. 2013. PMID: 24279384 Free PMC article.
IL-15: a novel prosurvival signaling pathway in cardiomyocytes.
Yeghiazarians Y, Honbo N, Imhof I, Woods B, Aguilera V, Ye J, Boyle AJ, Karliner JS. Yeghiazarians Y, et al. Among authors: ye j. J Cardiovasc Pharmacol. 2014 May;63(5):406-11. doi: 10.1097/FJC.0000000000000061. J Cardiovasc Pharmacol. 2014. PMID: 24805144 Free PMC article.
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