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Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques.
Nagatake T, Kishino S, Urano E, Murakami H, Kitamura N, Konishi K, Ohno H, Tiwari P, Morimoto S, Node E, Adachi J, Abe Y, Isoyama J, Sawane K, Honda T, Inoue A, Uwamizu A, Matsuzaka T, Miyamoto Y, Hirata SI, Saika A, Shibata Y, Hosomi K, Matsunaga A, Shimano H, Arita M, Aoki J, Oka M, Matsutani A, Tomonaga T, Kabashima K, Miyachi M, Yasutomi Y, Ogawa J, Kunisawa J. Nagatake T, et al. Among authors: yasutomi y. Mucosal Immunol. 2022 Feb;15(2):289-300. doi: 10.1038/s41385-021-00477-5. Epub 2022 Jan 10. Mucosal Immunol. 2022. PMID: 35013573 Free PMC article.
Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques.
Fukuyama Y, Yuki Y, Katakai Y, Harada N, Takahashi H, Takeda S, Mejima M, Joo S, Kurokawa S, Sawada S, Shibata H, Park EJ, Fujihashi K, Briles DE, Yasutomi Y, Tsukada H, Akiyoshi K, Kiyono H. Fukuyama Y, et al. Among authors: yasutomi y. Mucosal Immunol. 2015 Sep;8(5):1144-53. doi: 10.1038/mi.2015.5. Epub 2015 Feb 11. Mucosal Immunol. 2015. PMID: 25669148 Free PMC article.
The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.
Nagatake T, Shiogama Y, Inoue A, Kikuta J, Honda T, Tiwari P, Kishi T, Yanagisawa A, Isobe Y, Matsumoto N, Shimojou M, Morimoto S, Suzuki H, Hirata SI, Steneberg P, Edlund H, Aoki J, Arita M, Kiyono H, Yasutomi Y, Ishii M, Kabashima K, Kunisawa J. Nagatake T, et al. Among authors: yasutomi y. J Allergy Clin Immunol. 2018 Aug;142(2):470-484.e12. doi: 10.1016/j.jaci.2017.09.053. Epub 2017 Dec 27. J Allergy Clin Immunol. 2018. PMID: 29288079 Free article.
Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice.
Nagatake T, Suzuki H, Hirata SI, Matsumoto N, Wada Y, Morimoto S, Nasu A, Shimojou M, Kawano M, Ogami K, Tsujimura Y, Kuroda E, Iijima N, Hosomi K, Ishii KJ, Nosaka T, Yasutomi Y, Kunisawa J. Nagatake T, et al. Among authors: yasutomi y. Int Immunol. 2018 Sep 25;30(10):471-481. doi: 10.1093/intimm/dxy046. Int Immunol. 2018. PMID: 30011025 Free PMC article.
Vaccination with Intradermal Bacillus Calmette-Guérin Provides Robust Protection against Extrapulmonary Tuberculosis but Not Pulmonary Infection in Cynomolgus Macaques.
Tsujimura Y, Shiogama Y, Soma S, Okamura T, Takano J, Urano E, Murakata Y, Kawano A, Yamakawa N, Asaka MN, Matsuo K, Yasutomi Y. Tsujimura Y, et al. Among authors: yasutomi y. J Immunol. 2020 Dec 1;205(11):3023-3036. doi: 10.4049/jimmunol.2000386. Epub 2020 Oct 23. J Immunol. 2020. PMID: 33097574
COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions.
Urano E, Okamura T, Ono C, Ueno S, Nagata S, Kamada H, Higuchi M, Furukawa M, Kamitani W, Matsuura Y, Kawaoka Y, Yasutomi Y. Urano E, et al. Among authors: yasutomi y. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2104847118. doi: 10.1073/pnas.2104847118. Proc Natl Acad Sci U S A. 2021. PMID: 34625475 Free PMC article.
Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Onishi M, Ozasa K, Kobiyama K, Ohata K, Kitano M, Taniguchi K, Homma T, Kobayashi M, Sato A, Katakai Y, Yasutomi Y, Wijaya E, Igarashi Y, Nakatsu N, Ise W, Inoue T, Yamada H, Vandenbon A, Standley DM, Kurosaki T, Coban C, Aoshi T, Kuroda E, Ishii KJ. Onishi M, et al. Among authors: yasutomi y. J Immunol. 2015 Mar 15;194(6):2673-82. doi: 10.4049/jimmunol.1402027. Epub 2015 Feb 13. J Immunol. 2015. PMID: 25681338 Free PMC article.
180 results