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Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma.
Yarova PL, Stewart AL, Sathish V, Britt RD Jr, Thompson MA, P Lowe AP, Freeman M, Aravamudan B, Kita H, Brennan SC, Schepelmann M, Davies T, Yung S, Cholisoh Z, Kidd EJ, Ford WR, Broadley KJ, Rietdorf K, Chang W, Bin Khayat ME, Ward DT, Corrigan CJ, T Ward JP, Kemp PJ, Pabelick CM, Prakash YS, Riccardi D. Yarova PL, et al. Sci Transl Med. 2015 Apr 22;7(284):284ra60. doi: 10.1126/scitranslmed.aaa0282. Epub 2015 Apr 22. Sci Transl Med. 2015. PMID: 25904744 Free PMC article.
The calcium-sensing receptor: one of a kind.
Lopez-Fernandez I, Schepelmann M, Brennan SC, Yarova PL, Riccardi D. Lopez-Fernandez I, et al. Among authors: yarova pl. Exp Physiol. 2015 Dec;100(12):1392-9. doi: 10.1113/EP085137. Epub 2015 Jul 26. Exp Physiol. 2015. PMID: 26105576 Free article. Review. No abstract available.
Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma.
Yarova PL, Huang P, Schepelmann MW, Bruce R, Ecker R, Nica R, Telezhkin V, Traini D, Gomes Dos Reis L, Kidd EJ, Ford WR, Broadley KJ, Kariuki BM, Corrigan CJ, Ward JPT, Kemp PJ, Riccardi D. Yarova PL, et al. J Pharmacol Exp Ther. 2021 Jan;376(1):51-63. doi: 10.1124/jpet.120.000281. Epub 2020 Oct 28. J Pharmacol Exp Ther. 2021. PMID: 33115824
The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure.
Schepelmann M, Yarova PL, Lopez-Fernandez I, Davies TS, Brennan SC, Edwards PJ, Aggarwal A, Graça J, Rietdorf K, Matchkov V, Fenton RA, Chang W, Krssak M, Stewart A, Broadley KJ, Ward DT, Price SA, Edwards DH, Kemp PJ, Riccardi D. Schepelmann M, et al. Among authors: yarova pl. Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C193-204. doi: 10.1152/ajpcell.00248.2015. Epub 2015 Nov 4. Am J Physiol Cell Physiol. 2016. PMID: 26538090 Free PMC article.
Impaired Mineral Ion Metabolism in a Mouse Model of Targeted Calcium-Sensing Receptor (CaSR) Deletion from Vascular Smooth Muscle Cells.
Schepelmann M, Ranieri M, Lopez-Fernandez I, Webberley TS, Brennan SC, Yarova PL, Graca J, Hanif UK, Müller C, Manhardt T, Salzmann M, Quasnichka H, Price SA, Ward DT, Gilbert T, Matchkov VV, Fenton RA, Herberger A, Hwong J, Santa Maria C, Tu CL, Kallay E, Valenti G, Chang W, Riccardi D. Schepelmann M, et al. Among authors: yarova pl. J Am Soc Nephrol. 2022 Jul;33(7):1323-1340. doi: 10.1681/ASN.2021040585. Epub 2022 May 17. J Am Soc Nephrol. 2022. PMID: 35581010 Free PMC article.
Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA.
Kemp PJ, Rushton DJ, Yarova PL, Schnell C, Geater C, Hancock JM, Wieland A, Hughes A, Badder L, Cope E, Riccardi D, Randall AD, Brown JT, Allen ND, Telezhkin V. Kemp PJ, et al. Among authors: yarova pl. J Physiol. 2016 Nov 15;594(22):6583-6594. doi: 10.1113/JP270655. J Physiol. 2016. PMID: 27616476 Free PMC article. Review.
Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.
Telezhkin V, Schnell C, Yarova P, Yung S, Cope E, Hughes A, Thompson BA, Sanders P, Geater C, Hancock JM, Joy S, Badder L, Connor-Robson N, Comella A, Straccia M, Bombau G, Brown JT, Canals JM, Randall AD, Allen ND, Kemp PJ. Telezhkin V, et al. Am J Physiol Cell Physiol. 2016 Apr 1;310(7):C520-41. doi: 10.1152/ajpcell.00166.2015. Epub 2015 Dec 30. Am J Physiol Cell Physiol. 2016. PMID: 26718628 Free article.
18 results