Yap FYT - Search Results

1

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition).

Zhuang A, Yap FYT, Borg DJ, McCarthy D, Fotheringham A, Leung S, Penfold SA, Sourris KC, Coughlan MT, Schulz BL, Forbes JM. Zhuang A, et al. Among authors: yap fyt. Endocrinol Diabetes Metab. 2021 Jun 22;4(3):e00278. doi: 10.1002/edm2.278. eCollection 2021 Jul. Endocrinol Diabetes Metab. 2021. PMID: 34277994 Free PMC article.

2

Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.

Thallas-Bonke V, Thorpe SR, Coughlan MT, Fukami K, Yap FY, Sourris KC, Penfold SA, Bach LA, Cooper ME, Forbes JM. Thallas-Bonke V, et al. Diabetes. 2008 Feb;57(2):460-9. doi: 10.2337/db07-1119. Epub 2007 Oct 24. Diabetes. 2008. PMID: 17959934

3

Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy.

Sourris KC, Harcourt BE, Penfold SA, Yap FY, Morley AL, Morgan PE, Davies MJ, Baker ST, Jerums G, Forbes JM. Sourris KC, et al. Exp Diabetes Res. 2010;2010:974681. doi: 10.1155/2010/974681. Epub 2011 Jan 5. Exp Diabetes Res. 2010. PMID: 21318189 Free PMC article.

4

Advanced glycation end products are direct modulators of β-cell function.

Coughlan MT, Yap FY, Tong DC, Andrikopoulos S, Gasser A, Thallas-Bonke V, Webster DE, Miyazaki J, Kay TW, Slattery RM, Kaye DM, Drew BG, Kingwell BA, Fourlanos S, Groop PH, Harrison LC, Knip M, Forbes JM. Coughlan MT, et al. Diabetes. 2011 Oct;60(10):2523-32. doi: 10.2337/db10-1033. Epub 2011 Sep 12. Diabetes. 2011. PMID: 21911745 Free PMC article.

5

Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes.

Tesch G, Sourris KC, Summers SA, McCarthy D, Ward MS, Borg DJ, Gallo LA, Fotheringham AK, Pettit AR, Yap FY, Harcourt BE, Tan AL, Kausman JY, Nikolic-Paterson D, Kitching AR, Forbes JM. Tesch G, et al. Diabetologia. 2014 Sep;57(9):1977-85. doi: 10.1007/s00125-014-3291-z. Epub 2014 Jun 24. Diabetologia. 2014. PMID: 24957662

6

Increased liver AGEs induce hepatic injury mediated through an OST48 pathway.

Zhuang A, Yap FY, Bruce C, Leung C, Plan MR, Sullivan MA, Herath C, McCarthy D, Sourris KC, Kantharidis P, Coughlan MT, Febbraio MA, Hodson MP, Watt MJ, Angus P, Schulz BL, Forbes JM. Zhuang A, et al. Sci Rep. 2017 Sep 25;7(1):12292. doi: 10.1038/s41598-017-12548-4. Sci Rep. 2017. PMID: 28947796 Free PMC article.

7

Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion.

Zhuang A, Yap FYT, McCarthy D, Leung C, Sourris KC, Penfold SA, Thallas-Bonke V, Coughlan MT, Schulz BL, Forbes JM. Zhuang A, et al. Among authors: yap fyt. Sci Rep. 2019 Sep 20;9(1):13664. doi: 10.1038/s41598-019-50221-0. Sci Rep. 2019. PMID: 31541173 Free PMC article.

8

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.

Forbes JM, Söderlund J, Yap FY, Knip M, Andrikopoulos S, Ilonen J, Simell O, Veijola R, Sourris KC, Coughlan MT, Forsblom C, Slattery R, Grey ST, Wessman M, Yamamoto H, Bierhaus A, Cooper ME, Groop PH. Forbes JM, et al. Diabetologia. 2011 May;54(5):1032-42. doi: 10.1007/s00125-011-2058-z. Epub 2011 Feb 6. Diabetologia. 2011. PMID: 21298413

9

Advanced glycation end products as environmental risk factors for the development of type 1 diabetes.

Yap FY, Kantharidis P, Coughlan MT, Slattery R, Forbes JM. Yap FY, et al. Curr Drug Targets. 2012 Apr;13(4):526-40. doi: 10.2174/138945012799499758. Curr Drug Targets. 2012. PMID: 22250649 Review.

10

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction.

Borg DJ, Yap FYT, Keshvari S, Simmons DG, Gallo LA, Fotheringham AK, Zhuang A, Slattery RM, Hasnain SZ, Coughlan MT, Kantharidis P, Forbes JM. Borg DJ, et al. Among authors: yap fyt. Islets. 2018 Jan 2;10(1):10-24. doi: 10.1080/19382014.2017.1405189. Epub 2017 Dec 22. Islets. 2018. PMID: 29157116 Free PMC article.

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