Yang ZX - Search Results

1

Decoding the complexity of on-target integration: characterizing DNA insertions at the CRISPR-Cas9 targeted locus using nanopore sequencing.

Zhao JJ, Sun XY, Tian SN, Zhao ZZ, Yin MD, Zhao M, Zhang F, Li SA, Yang ZX, Wen W, Cheng T, Gong A, Zhang JP, Zhang XB. Zhao JJ, et al. Among authors: yang zx. BMC Genomics. 2024 Feb 17;25(1):189. doi: 10.1186/s12864-024-10050-6. BMC Genomics. 2024. PMID: 38368357 Free PMC article.

2

Dynamics and competition of CRISPR-Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing.

Fu YW, Dai XY, Wang WT, Yang ZX, Zhao JJ, Zhang JP, Wen W, Zhang F, Oberg KC, Zhang L, Cheng T, Zhang XB. Fu YW, et al. Among authors: yang zx. Nucleic Acids Res. 2021 Jan 25;49(2):969-985. doi: 10.1093/nar/gkaa1251. Nucleic Acids Res. 2021. PMID: 33398341 Free PMC article.

3

Effective control of large deletions after double-strand breaks by homology-directed repair and dsODN insertion.

Wen W, Quan ZJ, Li SA, Yang ZX, Fu YW, Zhang F, Li GH, Zhao M, Yin MD, Xu J, Zhang JP, Cheng T, Zhang XB. Wen W, et al. Among authors: yang zx. Genome Biol. 2021 Aug 20;22(1):236. doi: 10.1186/s13059-021-02462-4. Genome Biol. 2021. PMID: 34416913 Free PMC article.

4

GREPore-seq: A Robust Workflow to Detect Changes After Gene Editing Through Long-range PCR and Nanopore Sequencing.

Quan ZJ, Li SA, Yang ZX, Zhao JJ, Li GH, Zhang F, Wen W, Cheng T, Zhang XB. Quan ZJ, et al. Among authors: yang zx. Genomics Proteomics Bioinformatics. 2023 Dec;21(6):1221-1236. doi: 10.1016/j.gpb.2022.06.002. Epub 2022 Jun 23. Genomics Proteomics Bioinformatics. 2023. PMID: 35752289 Free PMC article.

5

High-Level Precise Knockin of iPSCs by Simultaneous Reprogramming and Genome Editing of Human Peripheral Blood Mononuclear Cells.

Wen W, Cheng X, Fu Y, Meng F, Zhang JP, Zhang L, Li XL, Yang Z, Xu J, Zhang F, Botimer GD, Yuan W, Sun C, Cheng T, Zhang XB. Wen W, et al. Stem Cell Reports. 2018 Jun 5;10(6):1821-1834. doi: 10.1016/j.stemcr.2018.04.013. Epub 2018 May 10. Stem Cell Reports. 2018. PMID: 29754960 Free PMC article.

6

Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse.

Zhang JP, Cheng XX, Zhao M, Li GH, Xu J, Zhang F, Yin MD, Meng FY, Dai XY, Fu YW, Yang ZX, Arakaki C, Su RJ, Wen W, Wang WT, Chen W, Choi H, Wang C, Gao G, Zhang L, Cheng T, Zhang XB. Zhang JP, et al. Among authors: yang zx. Genome Biol. 2019 Dec 16;20(1):276. doi: 10.1186/s13059-019-1907-9. Genome Biol. 2019. PMID: 31843008 Free PMC article.

7

HDAC inhibitors improve CRISPR-mediated HDR editing efficiency in iPSCs.

Zhang JP, Yang ZX, Zhang F, Fu YW, Dai XY, Wen W, Zhang B, Choi H, Chen W, Brown M, Baylink D, Zhang L, Qiu H, Wang C, Cheng T, Zhang XB. Zhang JP, et al. Among authors: yang zx. Sci China Life Sci. 2021 Sep;64(9):1449-1462. doi: 10.1007/s11427-020-1855-4. Epub 2021 Jan 6. Sci China Life Sci. 2021. PMID: 33420926

8

Improved and Flexible HDR Editing by Targeting Introns in iPSCs.

Fu J, Fu YW, Zhao JJ, Yang ZX, Li SA, Li GH, Quan ZJ, Zhang F, Zhang JP, Zhang XB, Sun CK. Fu J, et al. Among authors: yang zx. Stem Cell Rev Rep. 2022 Jun;18(5):1822-1833. doi: 10.1007/s12015-022-10331-1. Epub 2022 Jan 28. Stem Cell Rev Rep. 2022. PMID: 35089463 Free PMC article.

9

Superior Fidelity and Distinct Editing Outcomes of SaCas9 Compared with SpCas9 in Genome Editing.

Yang ZX, Fu YW, Zhao JJ, Zhang F, Li SA, Zhao M, Wen W, Zhang L, Cheng T, Zhang JP, Zhang XB. Yang ZX, et al. Genomics Proteomics Bioinformatics. 2023 Dec;21(6):1206-1220. doi: 10.1016/j.gpb.2022.12.003. Epub 2022 Dec 20. Genomics Proteomics Bioinformatics. 2023. PMID: 36549468 Free PMC article.

10

Reprogramming of human peripheral blood mononuclear cells into induced mesenchymal stromal cells using non-integrating vectors.

Chen W, Wang C, Yang ZX, Zhang F, Wen W, Schaniel C, Mi X, Bock M, Zhang XB, Qiu H, Wang C. Chen W, et al. Among authors: yang zx. Commun Biol. 2023 Apr 11;6(1):393. doi: 10.1038/s42003-023-04737-x. Commun Biol. 2023. PMID: 37041280 Free PMC article.

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