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Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma.
Ye Z, Ai X, Yang K, Yang Z, Fei F, Liao X, Qiu Z, Gimple RC, Yuan H, Huang H, Gong Y, Xiao C, Yue J, Huang L, Saulnier O, Wang W, Zhang P, Dai L, Wang X, Wang X, Ahn YH, You C, Xu J, Wan X, Taylor MD, Zhao L, Rich JN, Zhou S. Ye Z, et al. Among authors: yang k, yang z. Cancer Discov. 2023 Apr 3;13(4):974-1001. doi: 10.1158/2159-8290.CD-22-0455. Cancer Discov. 2023. PMID: 36649564 Free PMC article.
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.
Zhao L, Qiu Z, Yang Z, Xu L, Pearce TM, Wu Q, Yang K, Li F, Saulnier O, Fei F, Yu H, Gimple RC, Varadharajan V, Liu J, Hendrikse LD, Fong V, Wang W, Zhang J, Lv D, Lee D, Lehrich BM, Jin C, Ouyang L, Dixit D, Wu H, Wang X, Sloan AE, Wang X, Huan T, Mark Brown J, Goldman SA, Taylor MD, Zhou S, Rich JN. Zhao L, et al. Among authors: yang k, yang z. Nat Cancer. 2024 Jan;5(1):147-166. doi: 10.1038/s43018-023-00658-0. Epub 2024 Jan 3. Nat Cancer. 2024. PMID: 38172338
Activation of ERβ hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer.
Wang D, Tang M, Zhang P, Yang K, Huang L, Wu M, Shen Q, Yue J, Wang W, Gong Y, Warner M, Dai L, He H, Yang Z, Gustafsson JA, Zhou S. Wang D, et al. Among authors: yang k, yang z. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2306814121. doi: 10.1073/pnas.2306814121. Epub 2024 Mar 21. Proc Natl Acad Sci U S A. 2024. PMID: 38513102 Free PMC article.
Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51.
Tao L, Zhou Y, Pan X, Luo Y, Qiu J, Zhou X, Chen Z, Li Y, Xu L, Zhou Y, Zuo Z, Liu C, Wang L, Liu X, Tian X, Su N, Yang Z, Zhang Y, Gou K, Sang N, Liu H, Zou J, Xiao Y, Zhong X, Xu J, Yang X, Xiao K, Liu Y, Yang S, Peng Y, Han J, Cen X, Zhao Y. Tao L, et al. Among authors: yang s, yang x, yang z. Nat Commun. 2023 Nov 16;14(1):7430. doi: 10.1038/s41467-023-42850-x. Nat Commun. 2023. PMID: 37973845 Free PMC article.
Epigenetics in ovarian cancer: premise, properties, and perspectives.
Yang Q, Yang Y, Zhou N, Tang K, Lau WB, Lau B, Wang W, Xu L, Yang Z, Huang S, Wang X, Yi T, Zhao X, Wei Y, Wang H, Zhao L, Zhou S. Yang Q, et al. Among authors: yang y, yang z. Mol Cancer. 2018 Jul 31;17(1):109. doi: 10.1186/s12943-018-0855-4. Mol Cancer. 2018. PMID: 30064416 Free PMC article. Review.
The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts.
Zhao L, Wang W, Huang S, Yang Z, Xu L, Yang Q, Zhou X, Wang J, Shen Q, Wang C, Le X, Feng M, Zhou N, Lau WB, Lau B, Yao S, Yi T, Wang X, Zhao X, Wei Y, Zhou S. Zhao L, et al. Among authors: yang q, yang z. Genome Biol. 2018 Mar 16;19(1):35. doi: 10.1186/s13059-018-1412-6. Genome Biol. 2018. PMID: 29548303 Free PMC article.
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