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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.
Baumgartner CK, Ebrahimi-Nik H, Iracheta-Vellve A, Hamel KM, Olander KE, Davis TGR, McGuire KA, Halvorsen GT, Avila OI, Patel CH, Kim SY, Kammula AV, Muscato AJ, Halliwill K, Geda P, Klinge KL, Xiong Z, Duggan R, Mu L, Yeary MD, Patti JC, Balon TM, Mathew R, Backus C, Kennedy DE, Chen A, Longenecker K, Klahn JT, Hrusch CL, Krishnan N, Hutchins CW, Dunning JP, Bulic M, Tiwari P, Colvin KJ, Chuong CL, Kohnle IC, Rees MG, Boghossian A, Ronan M, Roth JA, Wu MJ, Suermondt JSMT, Knudsen NH, Cheruiyot CK, Sen DR, Griffin GK, Golub TR, El-Bardeesy N, Decker JH, Yang Y, Guffroy M, Fossey S, Trusk P, Sun IM, Liu Y, Qiu W, Sun Q, Paddock MN, Farney EP, Matulenko MA, Beauregard C, Frost JM, Yates KB, Kym PR, Manguso RT. Baumgartner CK, et al. Among authors: yang y. Nature. 2023 Oct;622(7984):850-862. doi: 10.1038/s41586-023-06575-7. Epub 2023 Oct 4. Nature. 2023. PMID: 37794185 Free PMC article.
Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.
Li Z, Wang C, Wang Z, Zhu C, Li J, Sha T, Ma L, Gao C, Yang Y, Sun Y, Wang J, Sun X, Lu C, Difiglia M, Mei Y, Ding C, Luo S, Dang Y, Ding Y, Fei Y, Lu B. Li Z, et al. Among authors: yang y. Nature. 2019 Nov;575(7781):203-209. doi: 10.1038/s41586-019-1722-1. Epub 2019 Oct 30. Nature. 2019. PMID: 31666698
Minutes-duration optical flares with supernova luminosities.
Ho AYQ, Perley DA, Chen P, Schulze S, Dhillon V, Kumar H, Suresh A, Swain V, Bremer M, Smartt SJ, Anderson JP, Anupama GC, Awiphan S, Barway S, Bellm EC, Ben-Ami S, Bhalerao V, de Boer T, Brink TG, Burruss R, Chandra P, Chen TW, Chen WP, Cooke J, Coughlin MW, Das KK, Drake AJ, Filippenko AV, Freeburn J, Fremling C, Fulton MD, Gal-Yam A, Galbany L, Gao H, Graham MJ, Gromadzki M, Gutiérrez CP, Hinds KR, Inserra C, A J N, Karambelkar V, Kasliwal MM, Kulkarni S, Müller-Bravo TE, Magnier EA, Mahabal AA, Moore T, Ngeow CC, Nicholl M, Ofek EO, Omand CMB, Onori F, Pan YC, Pessi PJ, Petitpas G, Polishook D, Poshyachinda S, Pursiainen M, Riddle R, Rodriguez AC, Rusholme B, Segre E, Sharma Y, Smith KW, Sollerman J, Srivastav S, Strotjohann NL, Suhr M, Svinkin D, Wang Y, Wiseman P, Wold A, Yang S, Yang Y, Yao Y, Young DR, Zheng W. Ho AYQ, et al. Among authors: yang s, yang y. Nature. 2023 Nov;623(7989):927-931. doi: 10.1038/s41586-023-06673-6. Epub 2023 Nov 15. Nature. 2023. PMID: 37968403 Free article.
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