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Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models.
Qi M, Fan S, Huang M, Pan J, Li Y, Miao Q, Lyu W, Li X, Deng L, Qiu S, Liu T, Deng W, Chu X, Jiang C, He W, Xia L, Yang Y, Hong J, Qi Q, Yin W, Liu X, Shi C, Chen M, Ye W, Zhang D. Qi M, et al. Among authors: yang y. J Clin Invest. 2022 Oct 3;132(19):e157399. doi: 10.1172/JCI157399. J Clin Invest. 2022. PMID: 35951441 Free PMC article.
Perivascular cell-derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs.
Huang M, Chen M, Qi M, Ye G, Pan J, Shi C, Yang Y, Zhao L, Mo X, Zhang Y, Li Y, Zhong J, Lu W, Li X, Zhang J, Lin J, Luo L, Liu T, Tang PM, Hong A, Cao Y, Ye W, Zhang D. Huang M, et al. Among authors: yang y. J Extracell Vesicles. 2021 May;10(7):e12096. doi: 10.1002/jev2.12096. Epub 2021 May 21. J Extracell Vesicles. 2021. PMID: 34035882 Free PMC article.
Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production.
Nakamura M, Zhang Y, Yang Y, Sonmez C, Zheng W, Huang G, Seki T, Iwamoto H, Ding B, Yin L, Foukakis T, Hatschek T, Li X, Hosaka K, Li J, Yu G, Wang X, Liu Y, Cao Y. Nakamura M, et al. Among authors: yang y. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9635-E9644. doi: 10.1073/pnas.1703431114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078273 Free PMC article.
Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance.
Iwamoto H, Abe M, Yang Y, Cui D, Seki T, Nakamura M, Hosaka K, Lim S, Wu J, He X, Sun X, Lu Y, Zhou Q, Shi W, Torimura T, Nie G, Li Q, Cao Y. Iwamoto H, et al. Among authors: yang y. Cell Metab. 2018 Jul 3;28(1):104-117.e5. doi: 10.1016/j.cmet.2018.05.005. Epub 2018 May 31. Cell Metab. 2018. PMID: 29861385 Free article.
Megakaryocytes Mediate Hyperglycemia-Induced Tumor Metastasis.
Wu B, Ye Y, Xie S, Li Y, Sun X, Lv M, Yang L, Cui N, Chen Q, Jensen LD, Cui D, Huang G, Zuo J, Zhang S, Liu W, Yang Y. Wu B, et al. Among authors: yang l, yang y. Cancer Res. 2021 Nov 1;81(21):5506-5522. doi: 10.1158/0008-5472.CAN-21-1180. Epub 2021 Sep 17. Cancer Res. 2021. PMID: 34535458
VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway.
Lee C, Chen R, Sun G, Liu X, Lin X, He C, Xing L, Liu L, Jensen LD, Kumar A, Langer HF, Ren X, Zhang J, Huang L, Yin X, Kim J, Zhu J, Huang G, Li J, Lu W, Chen W, Liu J, Hu J, Sun Q, Lu W, Fang L, Wang S, Kuang H, Zhang Y, Tian G, Mi J, Kang BA, Narazaki M, Prodeus A, Schoonjans L, Ornitz DM, Gariepy J, Eelen G, Dewerchin M, Yang Y, Ou JS, Mora A, Yao J, Zhao C, Liu Y, Carmeliet P, Cao Y, Li X. Lee C, et al. Among authors: yang y. Signal Transduct Target Ther. 2023 Aug 18;8(1):305. doi: 10.1038/s41392-023-01539-9. Signal Transduct Target Ther. 2023. PMID: 37591843 Free PMC article.
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