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IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.
Wang Q, Li D, Cao G, Shi Q, Zhu J, Zhang M, Cheng H, Wen Q, Xu H, Zhu L, Zhang H, Perry RJ, Spadaro O, Yang Y, He S, Chen Y, Wang B, Li G, Liu Z, Yang C, Wu X, Zhou L, Zhou Q, Ju Z, Lu H, Xin Y, Yang X, Wang C, Liu Y, Shulman GI, Dixit VD, Lu L, Yang H, Flavell RA, Yin Z. Wang Q, et al. Among authors: yang c, yang x, yang h, yang y. Nature. 2021 Dec;600(7888):314-318. doi: 10.1038/s41586-021-04127-5. Epub 2021 Nov 24. Nature. 2021. PMID: 34819664
Adipocyte OGT governs diet-induced hyperphagia and obesity.
Li MD, Vera NB, Yang Y, Zhang B, Ni W, Ziso-Qejvanaj E, Ding S, Zhang K, Yin R, Wang S, Zhou X, Fang EX, Xu T, Erion DM, Yang X. Li MD, et al. Among authors: yang x, yang y. Nat Commun. 2018 Nov 30;9(1):5103. doi: 10.1038/s41467-018-07461-x. Nat Commun. 2018. PMID: 30504766 Free PMC article.
OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance.
Yang Y, Li X, Luan HH, Zhang B, Zhang K, Nam JH, Li Z, Fu M, Munk A, Zhang D, Wang S, Liu Y, Albuquerque JP, Ong Q, Li R, Wang Q, Robert ME, Perry RJ, Chung D, Shulman GI, Yang X. Yang Y, et al. Among authors: yang x. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16616-16625. doi: 10.1073/pnas.1916121117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601203 Free PMC article.
O-GlcNAc transferase suppresses necroptosis and liver fibrosis.
Zhang B, Li MD, Yin R, Liu Y, Yang Y, Mitchell-Richards KA, Nam JH, Li R, Wang L, Iwakiri Y, Chung D, Robert ME, Ehrlich BE, Bennett AM, Yu J, Nathanson MH, Yang X. Zhang B, et al. Among authors: yang x, yang y. JCI Insight. 2019 Nov 1;4(21):e127709. doi: 10.1172/jci.insight.127709. JCI Insight. 2019. PMID: 31672932 Free PMC article.
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