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Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor.
Czepielewski RS, Erlich EC, Onufer EJ, Young S, Saunders BT, Han YH, Wohltmann M, Wang PL, Kim KW, Kumar S, Hsieh CS, Scallan JP, Yang Y, Zinselmeyer BH, Davis MJ, Randolph GJ. Czepielewski RS, et al. Among authors: yang y. Immunity. 2021 Dec 14;54(12):2795-2811.e9. doi: 10.1016/j.immuni.2021.10.003. Epub 2021 Nov 16. Immunity. 2021. PMID: 34788601 Free PMC article.
Lymphatic Vessel Network Structure and Physiology.
Breslin JW, Yang Y, Scallan JP, Sweat RS, Adderley SP, Murfee WL. Breslin JW, et al. Among authors: yang y. Compr Physiol. 2018 Dec 13;9(1):207-299. doi: 10.1002/cphy.c180015. Compr Physiol. 2018. PMID: 30549020 Free PMC article. Review.
Foxo1 deletion promotes the growth of new lymphatic valves.
Scallan JP, Knauer LA, Hou H, Castorena-Gonzalez JA, Davis MJ, Yang Y. Scallan JP, et al. Among authors: yang y. J Clin Invest. 2021 Jul 15;131(14):e142341. doi: 10.1172/JCI142341. J Clin Invest. 2021. PMID: 34263740 Free PMC article.
Rictor induces AKT signaling to regulate lymphatic valve formation.
Banerjee R, Knauer LA, Iyer D, Barlow SE, Scallan JP, Yang Y. Banerjee R, et al. Among authors: yang y. bioRxiv [Preprint]. 2023 Jun 13:2023.06.12.544698. doi: 10.1101/2023.06.12.544698. bioRxiv. 2023. PMID: 37397997 Free PMC article. Preprint.
VEGFR3 is required for button junction formation in lymphatic vessels.
Jannaway M, Iyer D, Mastrogiacomo DM, Li K, Sung DC, Yang Y, Kahn ML, Scallan JP. Jannaway M, et al. Among authors: yang y. Cell Rep. 2023 Jul 25;42(7):112777. doi: 10.1016/j.celrep.2023.112777. Epub 2023 Jul 16. Cell Rep. 2023. PMID: 37454290 Free PMC article.
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