Yang X - Search Results

1

Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.

Runfola M, Perni M, Yang X, Marchese M, Bacci A, Mero S, Santorelli FM, Polini B, Chiellini G, Giuliani D, Vilella A, Bodria M, Daini E, Vandini E, Rudge S, Gul S, Wakelam MOJ, Vendruscolo M, Rapposelli S. Runfola M, et al. Among authors: yang x. Pharmaceuticals (Basel). 2021 Dec 19;14(12):1330. doi: 10.3390/ph14121330. Pharmaceuticals (Basel). 2021. PMID: 34959730 Free PMC article.

2

Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation.

Joshi P, Chia S, Yang X, Perni M, Gabriel JM, Gilmer M, Limbocker R, Habchi J, Vendruscolo M. Joshi P, et al. Among authors: yang x. ACS Chem Neurosci. 2023 Feb 15;14(4):657-666. doi: 10.1021/acschemneuro.2c00523. Epub 2023 Feb 2. ACS Chem Neurosci. 2023. PMID: 36728544 Free PMC article.

3

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers.

Cohen SIA, Arosio P, Presto J, Kurudenkandy FR, Biverstal H, Dolfe L, Dunning C, Yang X, Frohm B, Vendruscolo M, Johansson J, Dobson CM, Fisahn A, Knowles TPJ, Linse S. Cohen SIA, et al. Among authors: yang x. Nat Struct Mol Biol. 2015 Mar;22(3):207-213. doi: 10.1038/nsmb.2971. Epub 2015 Feb 16. Nat Struct Mol Biol. 2015. PMID: 25686087 Free PMC article.

4

Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation.

Flagmeier P, De S, Michaels TCT, Yang X, Dear AJ, Emanuelsson C, Vendruscolo M, Linse S, Klenerman D, Knowles TPJ, Dobson CM. Flagmeier P, et al. Among authors: yang x. Nat Struct Mol Biol. 2020 Oct;27(10):886-891. doi: 10.1038/s41594-020-0471-z. Epub 2020 Aug 10. Nat Struct Mol Biol. 2020. PMID: 32778821

5

On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products.

Saar KL, Zhang Y, Müller T, Kumar CP, Devenish S, Lynn A, Łapińska U, Yang X, Linse S, Knowles TPJ. Saar KL, et al. Among authors: yang x. Lab Chip. 2017 Dec 19;18(1):162-170. doi: 10.1039/c7lc00797c. Lab Chip. 2017. PMID: 29192926

6

On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations.

Yang X, Meisl G, Frohm B, Thulin E, Knowles TPJ, Linse S. Yang X, et al. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5849-E5858. doi: 10.1073/pnas.1803539115. Epub 2018 Jun 12. Proc Natl Acad Sci U S A. 2018. PMID: 29895690 Free PMC article.

7

Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation.

Månsson C, van Cruchten RTP, Weininger U, Yang X, Cukalevski R, Arosio P, Dobson CM, Knowles T, Akke M, Linse S, Emanuelsson C. Månsson C, et al. Among authors: yang x. Biochemistry. 2018 Aug 14;57(32):4891-4902. doi: 10.1021/acs.biochem.8b00353. Epub 2018 Jul 30. Biochemistry. 2018. PMID: 30024736

8

Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide.

Meisl G, Yang X, Frohm B, Knowles TP, Linse S. Meisl G, et al. Among authors: yang x. Sci Rep. 2016 Jan 13;6:18728. doi: 10.1038/srep18728. Sci Rep. 2016. PMID: 26758487 Free PMC article.

9

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides.

Meisl G, Yang X, Hellstrand E, Frohm B, Kirkegaard JB, Cohen SI, Dobson CM, Linse S, Knowles TP. Meisl G, et al. Among authors: yang x. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9384-9. doi: 10.1073/pnas.1401564111. Epub 2014 Jun 17. Proc Natl Acad Sci U S A. 2014. PMID: 24938782 Free PMC article.

10

Obesity and lipid indices as predictors of depressive symptoms in middle-aged and elderly Chinese: insights from a nationwide cohort study.

Zhang X, Wang Y, Yang X, Li Y, Gui J, Mei Y, Liu H, Guo LL, Li J, Lei Y, Li X, Sun L, Yang L, Yuan T, Wang C, Zhang D, Li J, Liu M, Hua Y, Zhang L. Zhang X, et al. Among authors: yang x. BMC Psychiatry. 2024 May 10;24(1):351. doi: 10.1186/s12888-024-05806-z. BMC Psychiatry. 2024. PMID: 38730360

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