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Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems.
Wu H, Liu Q, Shi H, Xie J, Zhang Q, Ouyang Z, Li N, Yang Y, Liu Z, Zhao Y, Lai C, Ruan D, Peng J, Ge W, Chen F, Fan N, Jin Q, Liang Y, Lan T, Yang X, Wang X, Lei Z, Doevendans PA, Sluijter JPG, Wang K, Li X, Lai L. Wu H, et al. Among authors: yang x, yang y. Cell Mol Life Sci. 2018 Oct;75(19):3593-3607. doi: 10.1007/s00018-018-2810-3. Epub 2018 Apr 10. Cell Mol Life Sci. 2018. PMID: 29637228
Efficient base editing for multiple genes and loci in pigs using base editors.
Xie J, Ge W, Li N, Liu Q, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L. Xie J, et al. Among authors: yang x. Nat Commun. 2019 Jun 28;10(1):2852. doi: 10.1038/s41467-019-10421-8. Nat Commun. 2019. PMID: 31253764 Free PMC article.
Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.
Jin Q, Yang X, Gou S, Liu X, Zhuang Z, Liang Y, Shi H, Huang J, Wu H, Zhao Y, Ouyang Z, Zhang Q, Liu Z, Chen F, Ge W, Xie J, Li N, Lai C, Zhao X, Wang J, Lian M, Li L, Quan L, Ye Y, Lai L, Wang K. Jin Q, et al. Among authors: yang x. Sci China Life Sci. 2022 Nov;65(11):2269-2286. doi: 10.1007/s11427-021-2088-1. Epub 2022 May 18. Sci China Life Sci. 2022. PMID: 35596888
XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer.
Ruan D, Peng J, Wang X, Ouyang Z, Zou Q, Yang Y, Chen F, Ge W, Wu H, Liu Z, Zhao Y, Zhao B, Zhang Q, Lai C, Fan N, Zhou Z, Liu Q, Li N, Jin Q, Shi H, Xie J, Song H, Yang X, Chen J, Wang K, Li X, Lai L. Ruan D, et al. Among authors: yang x, yang y. Stem Cell Reports. 2018 Feb 13;10(2):494-508. doi: 10.1016/j.stemcr.2017.12.015. Epub 2018 Jan 11. Stem Cell Reports. 2018. PMID: 29337117 Free PMC article.
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