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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.
Viswanathan VS, Ryan MJ, Dhruv HD, Gill S, Eichhoff OM, Seashore-Ludlow B, Kaffenberger SD, Eaton JK, Shimada K, Aguirre AJ, Viswanathan SR, Chattopadhyay S, Tamayo P, Yang WS, Rees MG, Chen S, Boskovic ZV, Javaid S, Huang C, Wu X, Tseng YY, Roider EM, Gao D, Cleary JM, Wolpin BM, Mesirov JP, Haber DA, Engelman JA, Boehm JS, Kotz JD, Hon CS, Chen Y, Hahn WC, Levesque MP, Doench JG, Berens ME, Shamji AF, Clemons PA, Stockwell BR, Schreiber SL. Viswanathan VS, et al. Among authors: yang ws. Nature. 2017 Jul 27;547(7664):453-457. doi: 10.1038/nature23007. Epub 2017 Jul 5. Nature. 2017. PMID: 28678785 Free PMC article.
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels.
Yagoda N, von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ, Wolpaw AJ, Smukste I, Peltier JM, Boniface JJ, Smith R, Lessnick SL, Sahasrabudhe S, Stockwell BR. Yagoda N, et al. Among authors: yang ws. Nature. 2007 Jun 14;447(7146):864-8. doi: 10.1038/nature05859. Nature. 2007. PMID: 17568748 Free PMC article.
Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B 3rd, Stockwell BR. Dixon SJ, et al. Among authors: yang ws. Cell. 2012 May 25;149(5):1060-72. doi: 10.1016/j.cell.2012.03.042. Cell. 2012. PMID: 22632970 Free PMC article.
Regulation of ferroptotic cancer cell death by GPX4.
Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR. Yang WS, et al. Cell. 2014 Jan 16;156(1-2):317-331. doi: 10.1016/j.cell.2013.12.010. Cell. 2014. PMID: 24439385 Free PMC article.
804 results