Yang S - Search Results

1

Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer.

McAndrews KM, Chen Y, Darpolor JK, Zheng X, Yang S, Carstens JL, Li B, Wang H, Miyake T, Correa de Sampaio P, Kirtley ML, Natale M, Wu CC, Sugimoto H, LeBleu VS, Kalluri R. McAndrews KM, et al. Among authors: yang s. Cancer Discov. 2022 Jun 2;12(6):1580-1597. doi: 10.1158/2159-8290.CD-20-1484. Cancer Discov. 2022. PMID: 35348629 Free PMC article.

2

Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer.

Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, Melo SA, LeBleu VS, Kalluri R. Yang S, et al. Cancer Biol Ther. 2017 Mar 4;18(3):158-165. doi: 10.1080/15384047.2017.1281499. Epub 2017 Jan 25. Cancer Biol Ther. 2017. PMID: 28121262 Free PMC article.

3

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.

Kamerkar S, LeBleu VS, Sugimoto H, Yang S, Ruivo CF, Melo SA, Lee JJ, Kalluri R. Kamerkar S, et al. Among authors: yang s. Nature. 2017 Jun 22;546(7659):498-503. doi: 10.1038/nature22341. Epub 2017 Jun 7. Nature. 2017. PMID: 28607485 Free PMC article.

4

Generation and testing of clinical-grade exosomes for pancreatic cancer.

Mendt M, Kamerkar S, Sugimoto H, McAndrews KM, Wu CC, Gagea M, Yang S, Blanko EVR, Peng Q, Ma X, Marszalek JR, Maitra A, Yee C, Rezvani K, Shpall E, LeBleu VS, Kalluri R. Mendt M, et al. Among authors: yang s. JCI Insight. 2018 Apr 19;3(8):e99263. doi: 10.1172/jci.insight.99263. eCollection 2018 Apr 19. JCI Insight. 2018. PMID: 29669940 Free PMC article.

5

Type I collagen deletion in αSMA⁺ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer.

Chen Y, Kim J, Yang S, Wang H, Wu CJ, Sugimoto H, LeBleu VS, Kalluri R. Chen Y, et al. Among authors: yang s. Cancer Cell. 2021 Apr 12;39(4):548-565.e6. doi: 10.1016/j.ccell.2021.02.007. Epub 2021 Mar 4. Cancer Cell. 2021. PMID: 33667385 Free PMC article.

6

Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer.

Carstens JL, Yang S, Correa de Sampaio P, Zheng X, Barua S, McAndrews KM, Rao A, Burks JK, Rhim AD, Kalluri R. Carstens JL, et al. Among authors: yang s. Cell Rep. 2021 Apr 13;35(2):108990. doi: 10.1016/j.celrep.2021.108990. Cell Rep. 2021. PMID: 33852841 Free PMC article.

7

Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis.

Tang M, Chen Y, Li B, Sugimoto H, Yang S, Yang C, LeBleu VS, McAndrews KM, Kalluri R. Tang M, et al. Among authors: yang s, yang c. FASEB J. 2021 May;35(5):e21557. doi: 10.1096/fj.202002777RR. FASEB J. 2021. PMID: 33855751 Free PMC article.

8

Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta.

Chen Y, Yang S, Lovisa S, Ambrose CG, McAndrews KM, Sugimoto H, Kalluri R. Chen Y, et al. Among authors: yang s. Nat Commun. 2021 Dec 10;12(1):7199. doi: 10.1038/s41467-021-27563-3. Nat Commun. 2021. PMID: 34893625 Free PMC article.

9

Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer.

Chen Y, Yang S, Tavormina J, Tampe D, Zeisberg M, Wang H, Mahadevan KK, Wu CJ, Sugimoto H, Chang CC, Jenq RR, McAndrews KM, Kalluri R. Chen Y, et al. Among authors: yang s. Cancer Cell. 2022 Aug 8;40(8):818-834.e9. doi: 10.1016/j.ccell.2022.06.011. Epub 2022 Jul 21. Cancer Cell. 2022. PMID: 35868307 Free PMC article.

10

KRAS^G12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8⁺ T cells.

Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, Sugimoto H, Arian KA, Ying H, Barekatain Y, Sthanam LK, Kelly PJ, Maitra A, Heffernan TP, Kalluri R. Mahadevan KK, et al. Among authors: yang s. Cancer Cell. 2023 Sep 11;41(9):1606-1620.e8. doi: 10.1016/j.ccell.2023.07.002. Epub 2023 Aug 24. Cancer Cell. 2023. PMID: 37625401

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