Yang M - Search Results

1

Sortilin inhibits amyloid pathology by regulating non-specific degradation of APP.

Ruan CS, Liu J, Yang M, Saadipour K, Zeng YQ, Liao H, Wang YJ, Bobrovskaya L, Zhou XF. Ruan CS, et al. Among authors: yang m. Exp Neurol. 2018 Jan;299(Pt A):75-85. doi: 10.1016/j.expneurol.2017.10.018. Epub 2017 Oct 19. Exp Neurol. 2018. PMID: 29056359

2

The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking.

Yang M, Virassamy B, Vijayaraj SL, Lim Y, Saadipour K, Wang YJ, Han YC, Zhong JH, Morales CR, Zhou XF. Yang M, et al. PLoS One. 2013 May 21;8(5):e63049. doi: 10.1371/journal.pone.0063049. Print 2013. PLoS One. 2013. PMID: 23704887 Free PMC article.

3

Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway.

Saadipour K, Yang M, Lim Y, Georgiou K, Sun Y, Keating D, Liu J, Wang YR, Gai WP, Zhong JH, Wang YJ, Zhou XF. Saadipour K, et al. Among authors: yang m. J Neurochem. 2013 Oct;127(2):152-62. doi: 10.1111/jnc.12383. Epub 2013 Aug 22. J Neurochem. 2013. PMID: 23895422 Free article.

4

Effects of proNGF on neuronal viability, neurite growth and amyloid-beta metabolism.

Wang YJ, Valadares D, Sun Y, Wang X, Zhong JH, Liu XH, Majd S, Chen L, Gao CY, Chen S, Lim Y, Pollard A, Salegio EA, Gai WP, Yang M, Zhou XF. Wang YJ, et al. Among authors: yang m. Neurotox Res. 2010 Apr;17(3):257-67. doi: 10.1007/s12640-009-9098-x. Epub 2009 Aug 13. Neurotox Res. 2010. PMID: 19680737

5

Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with Huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processing.

Yang M, Lim Y, Li X, Zhong JH, Zhou XF. Yang M, et al. J Biol Chem. 2011 May 6;286(18):16272-84. doi: 10.1074/jbc.M110.195347. Epub 2011 Feb 28. J Biol Chem. 2011. PMID: 21357693 Free PMC article.

6

Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.

Yang GZ, Yang M, Lim Y, Lu JJ, Wang TH, Qi JG, Zhong JH, Zhou XF. Yang GZ, et al. Among authors: yang m. J Neurochem. 2012 Sep;122(5):1010-22. doi: 10.1111/j.1471-4159.2012.07845.x. J Neurochem. 2012. PMID: 22731248 Free article.

7

HAP1 Is Required for Endocytosis and Signalling of BDNF and Its Receptors in Neurons.

Lim Y, Wu LL, Chen S, Sun Y, Vijayaraj SL, Yang M, Bobrovskaya L, Keating D, Li XJ, Zhou XF. Lim Y, et al. Among authors: yang m. Mol Neurobiol. 2018 Mar;55(3):1815-1830. doi: 10.1007/s12035-016-0379-0. Epub 2017 Jan 12. Mol Neurobiol. 2018. PMID: 28083816 Free PMC article.

8

Intramuscular delivery of a single chain antibody gene prevents brain Aβ deposition and cognitive impairment in a mouse model of Alzheimer's disease.

Wang YJ, Gao CY, Yang M, Liu XH, Sun Y, Pollard A, Dong XY, Wu XB, Zhong JH, Zhou HD, Zhou XF. Wang YJ, et al. Among authors: yang m. Brain Behav Immun. 2010 Nov;24(8):1281-93. doi: 10.1016/j.bbi.2010.05.010. Epub 2010 Jun 2. Brain Behav Immun. 2010. PMID: 20595065

9

p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain.

Wang YJ, Wang X, Lu JJ, Li QX, Gao CY, Liu XH, Sun Y, Yang M, Lim Y, Evin G, Zhong JH, Masters C, Zhou XF. Wang YJ, et al. Among authors: yang m. J Neurosci. 2011 Feb 9;31(6):2292-304. doi: 10.1523/JNEUROSCI.2733-10.2011. J Neurosci. 2011. PMID: 21307265 Free PMC article.

10

p75NTR is mainly responsible for Aβ toxicity but not for its internalization: a primary study.

Yu H, Yang M, Wang Y, Xiao R, Zhou XF. Yu H, et al. Among authors: yang m. Neurol Sci. 2012 Oct;33(5):1043-50. doi: 10.1007/s10072-011-0892-x. Epub 2011 Dec 20. Neurol Sci. 2012. PMID: 22183269

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