Yang L - Search Results

1

A quantitative method for determination of colistin E2 methanesulphonate in human plasma by ¹⁵N-labeled colistin E2.

Xu H, Li Y, Zhang J, Zhang J, Lu J, Zhang X, Yang L, Zhao W, Feng J. Xu H, et al. Among authors: yang l. Sci Rep. 2023 Oct 26;13(1):18348. doi: 10.1038/s41598-023-45256-3. Sci Rep. 2023. PMID: 37884605 Free PMC article.

2

C-Aryl glucoside SGLT2 inhibitors containing a biphenyl motif as potential anti-diabetic agents.

Ding Y, Mao L, Xu D, Xie H, Yang L, Xu H, Geng W, Gao Y, Xia C, Zhang X, Meng Q, Wu D, Zhao J, Hu W. Ding Y, et al. Among authors: yang l. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2744-8. doi: 10.1016/j.bmcl.2015.05.040. Epub 2015 May 27. Bioorg Med Chem Lett. 2015. PMID: 26026363

3

Rapid generation of a novel DPP-4 inhibitor with long-acting properties: SAR study and PK/PD evaluation.

Xie H, Zeng S, He Y, Zhang G, Yu P, Zhong G, Xu H, Yang L, Wang S, Zhao X, Hu W. Xie H, et al. Among authors: yang l. Eur J Med Chem. 2017 Dec 1;141:519-529. doi: 10.1016/j.ejmech.2017.10.029. Epub 2017 Oct 12. Eur J Med Chem. 2017. PMID: 29078995

4

Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH.

Xiao H, Li P, Li X, He H, Wang J, Guo F, Zhang J, Wei L, Zhang H, Shi Y, Hou L, Shen L, Chen Z, Du C, Fu S, Zhang P, Hao F, Wang P, Xu D, Liang W, Tian X, Zhang A, Cheng X, Yang L, Wang X, Zhang X, Li J, Chen S. Xiao H, et al. Among authors: yang l. ACS Med Chem Lett. 2017 Oct 31;8(12):1246-1251. doi: 10.1021/acsmedchemlett.7b00318. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259742 Free PMC article.

5

Structure-activity relationship study of a series of caspase inhibitors containing γ-amino acid moiety for treatment of cholestatic liver disease.

Mou J, Wu S, Luo Z, Guo F, He H, Wang J, Lin F, Guo F, Sun J, Shen L, Zeng M, Wang C, Xu D, Gu Z, Tian X, Zhang A, Xu H, Yang L, Zhang X, Li J, Chen S. Mou J, et al. Among authors: yang l. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1874-1878. doi: 10.1016/j.bmcl.2018.04.002. Epub 2018 Apr 4. Bioorg Med Chem Lett. 2018. PMID: 29650287

6

Discovery of 4-Aminoquinoline-3-carboxamide Derivatives as Potent Reversible Bruton's Tyrosine Kinase Inhibitors for the Treatment of Rheumatoid Arthritis.

Yao X, Sun X, Jin S, Yang L, Xu H, Rao Y. Yao X, et al. Among authors: yang l. J Med Chem. 2019 Jul 25;62(14):6561-6574. doi: 10.1021/acs.jmedchem.9b00329. Epub 2019 Jul 12. J Med Chem. 2019. PMID: 31260299

7

Magnesium isoglycyrrhizinate alleviates fructose-induced liver oxidative stress and inflammatory injury through suppressing NOXs.

Yang YZ, Liu ZH, Wang SC, Zhang XQ, Xu HJ, Yang L, Kong LD. Yang YZ, et al. Among authors: yang l. Eur J Pharmacol. 2020 Sep 15;883:173314. doi: 10.1016/j.ejphar.2020.173314. Epub 2020 Jun 30. Eur J Pharmacol. 2020. PMID: 32619679

8

Discovery and preclinical evaluations of TQB3616, a novel CDK4-biased inhibitor.

Xu Z, Liu Y, Song B, Ren B, Xu X, Lin R, Zhu X, Chen C, Yang S, Zhu Y, Jiang W, Li W, Xia Y, Hu L, Chen S, Chan CC, Li J, Zhang X, Yang L, Tian X, Ding CZ. Xu Z, et al. Among authors: yang s, yang l. Bioorg Med Chem Lett. 2024 Apr 24;107:129769. doi: 10.1016/j.bmcl.2024.129769. Online ahead of print. Bioorg Med Chem Lett. 2024. PMID: 38670537

9

The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes.

Deng J, Peng L, Zhang G, Lan X, Li C, Chen F, Zhou Y, Lin Z, Chen L, Dai R, Xu H, Yang L, Zhang X, Hu W. Deng J, et al. Among authors: yang l. Eur J Med Chem. 2011 Jan;46(1):71-6. doi: 10.1016/j.ejmech.2010.10.016. Epub 2010 Oct 26. Eur J Med Chem. 2011. PMID: 21106276

10

Novel pyrrolopyrimidine analogues as potent dipeptidyl peptidase IV inhibitors based on pharmacokinetic property-driven optimization.

Xie H, Zeng L, Zeng S, Lu X, Zhang G, Zhao X, Cheng N, Tu Z, Li Z, Xu H, Yang L, Zhang X, Huang M, Zhao J, Hu W. Xie H, et al. Among authors: yang l. Eur J Med Chem. 2012 Jun;52:205-12. doi: 10.1016/j.ejmech.2012.03.015. Epub 2012 Mar 17. Eur J Med Chem. 2012. PMID: 22475866

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