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Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.
Altay O, Arif M, Li X, Yang H, Aydın M, Alkurt G, Kim W, Akyol D, Zhang C, Dinler-Doganay G, Turkez H, Shoaie S, Nielsen J, Borén J, Olmuscelik O, Doganay L, Uhlén M, Mardinoglu A. Altay O, et al. Among authors: yang h. Adv Sci (Weinh). 2021 Sep;8(17):e2101222. doi: 10.1002/advs.202101222. Epub 2021 Jun 28. Adv Sci (Weinh). 2021. PMID: 34180141 Free PMC article. Clinical Trial.
Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.
Zeybel M, Altay O, Arif M, Li X, Yang H, Fredolini C, Akyildiz M, Saglam B, Gonenli MG, Ural D, Kim W, Schwenk JM, Zhang C, Shoaie S, Nielsen J, Uhlén M, Borén J, Mardinoglu A. Zeybel M, et al. Among authors: yang h. Mol Syst Biol. 2021 Oct;17(10):e10459. doi: 10.15252/msb.202110459. Mol Syst Biol. 2021. PMID: 34694070 Free PMC article. Clinical Trial.
Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis.
Zeybel M, Arif M, Li X, Altay O, Yang H, Shi M, Akyildiz M, Saglam B, Gonenli MG, Yigit B, Ulukan B, Ural D, Shoaie S, Turkez H, Nielsen J, Zhang C, Uhlén M, Borén J, Mardinoglu A. Zeybel M, et al. Among authors: yang h. Adv Sci (Weinh). 2022 Apr;9(11):e2104373. doi: 10.1002/advs.202104373. Epub 2022 Feb 7. Adv Sci (Weinh). 2022. PMID: 35128832 Free PMC article.
Chronic hyperinsulinemia promotes human hepatocyte senescence.
Baboota RK, Spinelli R, Erlandsson MC, Brandao BB, Lino M, Yang H, Mardinoglu A, Bokarewa MI, Boucher J, Kahn CR, Smith U. Baboota RK, et al. Among authors: yang h. Mol Metab. 2022 Oct;64:101558. doi: 10.1016/j.molmet.2022.101558. Epub 2022 Jul 21. Mol Metab. 2022. PMID: 35872305 Free PMC article.
Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.
Ambikan AT, Yang H, Krishnan S, Svensson Akusjärvi S, Gupta S, Lourda M, Sperk M, Arif M, Zhang C, Nordqvist H, Ponnan SM, Sönnerborg A, Treutiger CJ, O'Mahony L, Mardinoglu A, Benfeitas R, Neogi U. Ambikan AT, et al. Among authors: yang h. Cell Syst. 2022 Aug 17;13(8):665-681.e4. doi: 10.1016/j.cels.2022.06.006. Epub 2022 Jul 8. Cell Syst. 2022. PMID: 35933992 Free PMC article.
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning.
Zhang C, Shi M, Kim W, Arif M, Klevstig M, Li X, Yang H, Bayram C, Bolat I, Tozlu ÖÖ, Hacımuftuoglu A, Yıldırım S, Sebhaoui J, Iqbal S, Wei Y, Shi X, Nielsen J, Turkez H, Uhlen M, Boren J, Mardinoglu A. Zhang C, et al. Among authors: yang h. EBioMedicine. 2022 Sep;83:104214. doi: 10.1016/j.ebiom.2022.104214. Epub 2022 Aug 18. EBioMedicine. 2022. PMID: 35988463 Free PMC article.
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