Yang G - Search Results

1

Protein-level mutant p53 reporters identify druggable rare precancerous clones in noncancerous tissues.

Yao P, Xiao P, Huang Z, Tang M, Tang X, Yang G, Zhang Q, Li X, Yang Z, Xie C, Gong H, Wang G, Liu Y, Wang X, Li H, Jia D, Dai L, Chen L, Chen C, Liu Y, Xiao H, Zhang Y, Wang Y. Yao P, et al. Among authors: yang g, yang z. Nat Cancer. 2023 Aug;4(8):1176-1192. doi: 10.1038/s43018-023-00608-w. Epub 2023 Aug 3. Nat Cancer. 2023. PMID: 37537298

2

Spatial transcriptomics in development and disease.

Zhou R, Yang G, Zhang Y, Wang Y. Zhou R, et al. Among authors: yang g. Mol Biomed. 2023 Oct 9;4(1):32. doi: 10.1186/s43556-023-00144-0. Mol Biomed. 2023. PMID: 37806992 Free PMC article. Review.

3

Targeting Autophagy-Related Epigenetic Regulators for Cancer Drug Discovery.

Li Y, Yang G, Yang C, Tang P, Chen J, Zhang J, Liu J, Ouyang L. Li Y, et al. Among authors: yang c, yang g. J Med Chem. 2021 Aug 26;64(16):11798-11815. doi: 10.1021/acs.jmedchem.1c00579. Epub 2021 Aug 11. J Med Chem. 2021. PMID: 34378389

4

Discovery, Synthesis, and Evaluation of Novel Dual Inhibitors of a Vascular Endothelial Growth Factor Receptor and Poly(ADP-Ribose) Polymerase for BRCA Wild-Type Breast Cancer Therapy.

Li Y, Liu Y, Zhang D, Chen J, Yang G, Tang P, Yang C, Liu J, Zhang J, Ouyang L. Li Y, et al. Among authors: yang c, yang g. J Med Chem. 2023 Sep 14;66(17):12069-12100. doi: 10.1021/acs.jmedchem.3c00640. Epub 2023 Aug 24. J Med Chem. 2023. PMID: 37616488

5

Discovery, Synthesis, and Evaluation of Highly Selective Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) Inhibitor for the Potential Treatment of Metastatic Triple-Negative Breast Cancer.

Li Y, Yang G, Zhang J, Tang P, Yang C, Wang G, Chen J, Liu J, Zhang L, Ouyang L. Li Y, et al. Among authors: yang c, yang g. J Med Chem. 2021 Aug 26;64(16):12022-12048. doi: 10.1021/acs.jmedchem.1c00678. Epub 2021 Aug 5. J Med Chem. 2021. PMID: 34351741

6

Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.

Liu Y, Zhen Y, Wang G, Yang G, Fu L, Liu B, Ouyang L. Liu Y, et al. Among authors: yang g. Eur J Med Chem. 2020 Oct 15;204:112505. doi: 10.1016/j.ejmech.2020.112505. Epub 2020 Jul 18. Eur J Med Chem. 2020. PMID: 32717479

7

Discovery of 4-Hydroxyquinazoline Derivatives as Small Molecular BET/PARP1 Inhibitors That Induce Defective Homologous Recombination and Lead to Synthetic Lethality for Triple-Negative Breast Cancer Therapy.

Zhang J, Yang C, Tang P, Chen J, Zhang D, Li Y, Yang G, Liu Y, Zhang Y, Wang Y, Liu J, Ouyang L. Zhang J, et al. Among authors: yang c, yang g. J Med Chem. 2022 May 12;65(9):6803-6825. doi: 10.1021/acs.jmedchem.2c00135. Epub 2022 Apr 20. J Med Chem. 2022. PMID: 35442700

8

Targeting Atg4B for cancer therapy: Chemical mediators.

Yang G, Li Y, Zhao Y, Ouyang L, Chen Y, Liu B, Liu J. Yang G, et al. Eur J Med Chem. 2021 Jan 1;209:112917. doi: 10.1016/j.ejmech.2020.112917. Epub 2020 Oct 11. Eur J Med Chem. 2021. PMID: 33077263 Review.

9

Targeting Bromodomain-Selective Inhibitors of BET Proteins in Drug Discovery and Development.

Chen J, Tang P, Wang Y, Wang J, Yang C, Li Y, Yang G, Wu F, Zhang J, Ouyang L. Chen J, et al. Among authors: yang c, yang g. J Med Chem. 2022 Apr 14;65(7):5184-5211. doi: 10.1021/acs.jmedchem.1c01835. Epub 2022 Mar 24. J Med Chem. 2022. PMID: 35324195

10

Single-nucleus RNA transcriptome profiling reveals murine adipose tissue endothelial cell proliferation gene networks involved in obesity development.

Lu Z, Ding L, Jiang X, Zhang S, Yan M, Yang G, Tian X, Wang Q. Lu Z, et al. Among authors: yang g. Arch Biochem Biophys. 2024 May 8:110029. doi: 10.1016/j.abb.2024.110029. Online ahead of print. Arch Biochem Biophys. 2024. PMID: 38729594

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