Yang G - Search Results

1

PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.

Gao S, Li X, Jiang Q, Liang Q, Zhang F, Li S, Zhang R, Luan J, Zhu J, Gu X, Xiao T, Huang H, Chen S, Ning W, Yang G, Yang C, Zhou H. Gao S, et al. Among authors: yang c, yang g. Sci Adv. 2022 Sep 23;8(38):eabo0987. doi: 10.1126/sciadv.abo0987. Epub 2022 Sep 21. Sci Adv. 2022. PMID: 36129984 Free PMC article.

2

Problems and Solutions in Click Chemistry Applied to Drug Probes.

Zhong W, Sun B, Lu C, Yu H, Wang C, He L, Gu J, Chen S, Liu Y, Jing X, Bi Z, Yang G, Zhou H, Sun T, Yang C. Zhong W, et al. Among authors: yang c, yang g. Sci Rep. 2016 Oct 26;6:35579. doi: 10.1038/srep35579. Sci Rep. 2016. PMID: 27782133 Free PMC article.

3

Dihydroartemisinin inhibits EMT induced by platinum-based drugs via Akt-Snail pathway.

Qin Y, Yang G, Li M, Liu HJ, Zhong WL, Yan XQ, Qiao KL, Yang JH, Zhai DH, Yang W, Chen S, Zhou HG, Sun T, Yang C. Qin Y, et al. Among authors: yang c, yang jh, yang g, yang w. Oncotarget. 2017 Oct 10;8(61):103815-103827. doi: 10.18632/oncotarget.21793. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262602 Free PMC article.

4

α-Alkylation of Chiral Sulfinimines for Constructing Quaternary Chiral Carbons by Introducing Removable Directing Groups.

Qin S, Liu S, Cao Y, Li J, Chong C, Liu T, Luo Y, Hu J, Jiang S, Zhou H, Yang G, Yang C. Qin S, et al. Among authors: yang c, yang g. Org Lett. 2018 Mar 2;20(5):1350-1354. doi: 10.1021/acs.orglett.8b00105. Epub 2018 Feb 15. Org Lett. 2018. PMID: 29446637

5

A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway.

Liu S, Gao X, Zhang L, Qin S, Wei M, Liu N, Zhao R, Li B, Meng Y, Lin G, Lu C, Liu X, Xie M, Liu T, Zhou H, Qi M, Yang G, Yang C. Liu S, et al. Among authors: yang c, yang g. Eur J Med Chem. 2018 Aug 5;156:21-42. doi: 10.1016/j.ejmech.2018.06.046. Epub 2018 Jun 20. Eur J Med Chem. 2018. PMID: 30006166

6

Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.

Li X, Lu C, Liu S, Shuaishuai Liu, Su C, Xiao T, Bi Z, Sheng P, Huang M, Liu X, Wei Y, Zhao L, Miao S, Mao J, Huang K, Gao S, Liu N, Qi M, Liu T, Qin S, Wei L, Sun T, Ning W, Yang G, Zhou H, Yang C. Li X, et al. Among authors: yang c, yang g. Eur J Med Chem. 2018 Sep 5;157:229-247. doi: 10.1016/j.ejmech.2018.07.074. Epub 2018 Aug 3. Eur J Med Chem. 2018. PMID: 30096654

7

Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids.

Liu X, Li B, Zhang Z, Wei Y, Xu Z, Qin S, Liu N, Zhao R, Peng J, Yang G, Qi M, Liu T, Xie M, Liu S, Gao X, Lu C, Zhu L, Long X, Kang H, Sun T, Zhou H, Wei M, Yang G, Yang C. Liu X, et al. Among authors: yang c, yang g. J Med Chem. 2018 Dec 13;61(23):10814-10833. doi: 10.1021/acs.jmedchem.8b01445. Epub 2018 Nov 29. J Med Chem. 2018. PMID: 30433783

8

Discovery and Optimization of a Novel 2H-Pyrazolo[3,4-d]pyrimidine Derivative as a Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitor.

Wei Y, Tang Y, Zhou Y, Yang Y, Cui Y, Wang X, Wang Y, Liu Y, Liu N, Wang Q, Li C, Ruan H, Zhou H, Wei M, Yang G, Yang C. Wei Y, et al. Among authors: yang c, yang g, yang y. J Med Chem. 2021 Jul 8;64(13):9078-9099. doi: 10.1021/acs.jmedchem.1c00174. Epub 2021 Jun 15. J Med Chem. 2021. PMID: 34129329

9

5α-Epoxyalantolactone Inhibits Metastasis of Triple-Negative Breast Cancer Cells by Covalently Binding a Conserved Cysteine of Annexin A2.

Wei M, Zhou Y, Li C, Yang Y, Liu T, Liu Y, Wei Y, Liu N, Liu S, Wang Q, Cao S, Sun Y, Sheng P, Lu C, Yang C, Liu X, Yang G. Wei M, et al. Among authors: yang c, yang g, yang y. J Med Chem. 2021 Sep 9;64(17):12537-12547. doi: 10.1021/acs.jmedchem.1c00267. Epub 2021 Aug 5. J Med Chem. 2021. PMID: 34351142

10

Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.

Cao S, Ma L, Liu Y, Wei M, Yao Y, Li C, Wang R, Liu N, Dong Z, Li X, Li M, Wang X, Yang C, Yang G. Cao S, et al. Among authors: yang c, yang g. J Med Chem. 2021 Nov 25;64(22):16497-16511. doi: 10.1021/acs.jmedchem.1c00996. Epub 2021 Oct 25. J Med Chem. 2021. PMID: 34694800

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