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cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.
Ma H, Butler MR, Thapa A, Belcher J, Yang F, Baehr W, Biel M, Michalakis S, Ding XQ. Ma H, et al. Among authors: yang f. J Biol Chem. 2015 Aug 21;290(34):20880-20892. doi: 10.1074/jbc.M115.641159. Epub 2015 Jun 29. J Biol Chem. 2015. PMID: 26124274 Free PMC article.
Deficiency of type 2 iodothyronine deiodinase reduces necroptosis activity and oxidative stress responses in retinas of Leber congenital amaurosis model mice.
Yang F, Ma H, Butler MR, Ding XQ. Yang F, et al. FASEB J. 2018 Jun 6;32(11):fj201800484RR. doi: 10.1096/fj.201800484RR. Online ahead of print. FASEB J. 2018. PMID: 29874126 Free PMC article.
This work shows that suppression of TH signaling reduces cellular RIPK/necroptosis activity and oxidative stress responses in degenerating retinas, suggesting a mechanism underlying the observed cone preservation.-Yang, F., Ma, H., Butler, M. R., Ding, X.-Q. Deficie …
This work shows that suppression of TH signaling reduces cellular RIPK/necroptosis activity and oxidative stress responses in degenerating r …
Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration.
Yang F, Ma H, Belcher J, Butler MR, Redmond TM, Boye SL, Hauswirth WW, Ding XQ. Yang F, et al. FASEB J. 2016 Dec;30(12):4313-4325. doi: 10.1096/fj.201600715R. Epub 2016 Sep 13. FASEB J. 2016. PMID: 27623928 Free PMC article.
We show that targeting DIOs protects cones, and intracellular inhibition of TH components locally in the retina may represent a novel strategy for retinal degeneration management.-Yang, F., Ma, H., Belcher, J., Butler, M. R., Redmond, T. M., Boye, S. ...
We show that targeting DIOs protects cones, and intracellular inhibition of TH components locally in the retina may represent a novel strate …
21,840 results
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