Yang C - Search Results

1

Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.

Cao S, Ma L, Liu Y, Wei M, Yao Y, Li C, Wang R, Liu N, Dong Z, Li X, Li M, Wang X, Yang C, Yang G. Cao S, et al. Among authors: yang c, yang g. J Med Chem. 2021 Nov 25;64(22):16497-16511. doi: 10.1021/acs.jmedchem.1c00996. Epub 2021 Oct 25. J Med Chem. 2021. PMID: 34694800

2

Design, synthesis and evaluation of 1,2-benzisothiazol-3-one derivatives as potent caspase-3 inhibitors.

Liu D, Tian Z, Yan Z, Wu L, Ma Y, Wang Q, Liu W, Zhou H, Yang C. Liu D, et al. Among authors: yang c. Bioorg Med Chem. 2013 Jun 1;21(11):2960-7. doi: 10.1016/j.bmc.2013.03.075. Epub 2013 Apr 6. Bioorg Med Chem. 2013. PMID: 23632366

3

Simplified captopril analogues as NDM-1 inhibitors.

Li N, Xu Y, Xia Q, Bai C, Wang T, Wang L, He D, Xie N, Li L, Wang J, Zhou HG, Xu F, Yang C, Zhang Q, Yin Z, Guo Y, Chen Y. Li N, et al. Among authors: yang c. Bioorg Med Chem Lett. 2014 Jan 1;24(1):386-9. doi: 10.1016/j.bmcl.2013.10.068. Epub 2013 Nov 6. Bioorg Med Chem Lett. 2014. PMID: 24269122

4

Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors.

Liu W, Zhu HM, Niu GJ, Shi EZ, Chen J, Sun B, Chen WQ, Zhou HG, Yang C. Liu W, et al. Among authors: yang c. Bioorg Med Chem. 2014 Jan 1;22(1):292-302. doi: 10.1016/j.bmc.2013.11.028. Epub 2013 Nov 21. Bioorg Med Chem. 2014. PMID: 24316352 Free PMC article.

5

1,2-benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors.

Wu L, Lu M, Yan Z, Tang X, Sun B, Liu W, Zhou H, Yang C. Wu L, et al. Among authors: yang c. Bioorg Med Chem. 2014 Apr 15;22(8):2416-26. doi: 10.1016/j.bmc.2014.03.002. Epub 2014 Mar 12. Bioorg Med Chem. 2014. PMID: 24656804

6

Syntheses and biological evaluation of 1,2,3-triazole and 1,3,4-oxadiazole derivatives of imatinib.

Li YT, Wang JH, Pan CW, Meng FF, Chu XQ, Ding YH, Qu WZ, Li HY, Yang C, Zhang Q, Bai CG, Chen Y. Li YT, et al. Among authors: yang c. Bioorg Med Chem Lett. 2016 Mar 1;26(5):1419-27. doi: 10.1016/j.bmcl.2016.01.068. Epub 2016 Jan 23. Bioorg Med Chem Lett. 2016. PMID: 26850004

7

Problems and Solutions in Click Chemistry Applied to Drug Probes.

Zhong W, Sun B, Lu C, Yu H, Wang C, He L, Gu J, Chen S, Liu Y, Jing X, Bi Z, Yang G, Zhou H, Sun T, Yang C. Zhong W, et al. Among authors: yang c, yang g. Sci Rep. 2016 Oct 26;6:35579. doi: 10.1038/srep35579. Sci Rep. 2016. PMID: 27782133 Free PMC article.

8

Dihydroartemisinin inhibits EMT induced by platinum-based drugs via Akt-Snail pathway.

Qin Y, Yang G, Li M, Liu HJ, Zhong WL, Yan XQ, Qiao KL, Yang JH, Zhai DH, Yang W, Chen S, Zhou HG, Sun T, Yang C. Qin Y, et al. Among authors: yang c, yang jh, yang g, yang w. Oncotarget. 2017 Oct 10;8(61):103815-103827. doi: 10.18632/oncotarget.21793. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262602 Free PMC article.

9

α-Alkylation of Chiral Sulfinimines for Constructing Quaternary Chiral Carbons by Introducing Removable Directing Groups.

Qin S, Liu S, Cao Y, Li J, Chong C, Liu T, Luo Y, Hu J, Jiang S, Zhou H, Yang G, Yang C. Qin S, et al. Among authors: yang c, yang g. Org Lett. 2018 Mar 2;20(5):1350-1354. doi: 10.1021/acs.orglett.8b00105. Epub 2018 Feb 15. Org Lett. 2018. PMID: 29446637

10

A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway.

Liu S, Gao X, Zhang L, Qin S, Wei M, Liu N, Zhao R, Li B, Meng Y, Lin G, Lu C, Liu X, Xie M, Liu T, Zhou H, Qi M, Yang G, Yang C. Liu S, et al. Among authors: yang c, yang g. Eur J Med Chem. 2018 Aug 5;156:21-42. doi: 10.1016/j.ejmech.2018.06.046. Epub 2018 Jun 20. Eur J Med Chem. 2018. PMID: 30006166

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