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BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
Fu Y, Yang B, Cui Y, Hu X, Li X, Lu F, Qin T, Zhang L, Hu Z, Guo E, Fan J, Xiao R, Li W, Qin X, Hu D, Peng W, Liu J, Wang B, Mills GB, Chen G, Sun C. Fu Y, et al. Among authors: yang b. J Immunother Cancer. 2023 Apr;11(4):e006070. doi: 10.1136/jitc-2022-006070. J Immunother Cancer. 2023. PMID: 37072347 Free PMC article.
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer.
Wang H, Li N, Liu Q, Guo J, Pan Q, Cheng B, Xu J, Dong B, Yang G, Yang B, Wang X, Gu Y, Zhang G, Lian Y, Zhang W, Zhang M, Li T, Zang Y, Tan M, Li Q, Wang X, Yu Z, Jiang J, Huang H, Qin J. Wang H, et al. Among authors: yang b, yang g. Cancer Cell. 2023 Jul 10;41(7):1345-1362.e9. doi: 10.1016/j.ccell.2023.05.016. Epub 2023 Jun 22. Cancer Cell. 2023. PMID: 37352863
Concordance and Clinical Significance of Genomic Alterations in Progressive Tumor Tissue and Matched Circulating Tumor DNA in Aggressive-variant Prostate Cancer.
Wang R, Xu Q, Guo H, Yang G, Zhang J, Wang H, Xu T, Guo C, Yuan J, He Y, Zhang X, Fu H, Xu G, Zhao B, Xie J, Zhao T, Huang L, Zhang J, Peng B, Yao X, Yang B. Wang R, et al. Among authors: yang b, yang g. Cancer Res Commun. 2023 Nov 3;3(11):2221-2232. doi: 10.1158/2767-9764.CRC-23-0175. Cancer Res Commun. 2023. PMID: 37877742 Free PMC article.
Olaparib Combined with Abiraterone versus Olaparib Monotherapy for Patients with Metastatic Castration-resistant Prostate Cancer Progressing after Abiraterone and Harboring DNA Damage Repair Deficiency: A Multicenter Real-world Study.
Xie J, Guo H, Dong B, Chen W, Jin C, Xu Q, Ding L, Liu W, Dong S, Zhao T, Yu Y, Guo C, Yao X, Peng B, Yang B. Xie J, et al. Among authors: yang b. Eur Urol Oncol. 2024 Mar 7:S2588-9311(24)00050-6. doi: 10.1016/j.euo.2024.02.005. Online ahead of print. Eur Urol Oncol. 2024. PMID: 38458891
Sustained complete response to first-line immunochemotherapy for highly aggressive TP53/MDM2-mutated upper tract urothelial carcinoma with ERBB2 mutations, luminal immune-infiltrated contexture, and non-mesenchymal state: a case report and literature review.
Xu T, Guo H, Xie J, He Y, Che J, Peng B, Yang B, Yao X. Xu T, et al. Among authors: yang b. Front Oncol. 2023 Jun 23;13:1119343. doi: 10.3389/fonc.2023.1119343. eCollection 2023. Front Oncol. 2023. PMID: 37427135 Free PMC article.
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