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Nedd4 controls animal growth by regulating IGF-1 signaling.
Cao XR, Lill NL, Boase N, Shi PP, Croucher DR, Shan H, Qu J, Sweezer EM, Place T, Kirby PA, Daly RJ, Kumar S, Yang B. Cao XR, et al. Among authors: yang b. Sci Signal. 2008 Sep 23;1(38):ra5. doi: 10.1126/scisignal.1160940. Sci Signal. 2008. PMID: 18812566 Free PMC article.
Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2.
Shi PP, Cao XR, Sweezer EM, Kinney TS, Williams NR, Husted RF, Nair R, Weiss RM, Williamson RA, Sigmund CD, Snyder PM, Staub O, Stokes JB, Yang B. Shi PP, et al. Among authors: yang b. Am J Physiol Renal Physiol. 2008 Aug;295(2):F462-70. doi: 10.1152/ajprenal.90300.2008. Epub 2008 Jun 4. Am J Physiol Renal Physiol. 2008. PMID: 18524855 Free PMC article.
NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation.
Fang DF, He K, Wang N, Sang ZH, Qiu X, Xu G, Jian Z, Liang B, Li T, Li HY, Li AL, Zhou T, Gong WL, Yang B, Karin M, Zhang XM, Li WH. Fang DF, et al. Among authors: yang b. Nat Commun. 2014 Jul 29;5:4513. doi: 10.1038/ncomms5513. Nat Commun. 2014. PMID: 25072696 Free article.
Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.
Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O. Arroyo JP, et al. Among authors: yang b. J Am Soc Nephrol. 2011 Sep;22(9):1707-19. doi: 10.1681/ASN.2011020132. Epub 2011 Aug 18. J Am Soc Nephrol. 2011. PMID: 21852580 Free PMC article.
Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.
Clements JL, Lee JR, Gross B, Yang B, Olson JD, Sandra A, Watson SP, Lentz SR, Koretzky GA. Clements JL, et al. Among authors: yang b. J Clin Invest. 1999 Jan;103(1):19-25. doi: 10.1172/JCI5317. J Clin Invest. 1999. PMID: 9884330 Free PMC article.
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