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Clinical Activity and Exploratory Resistance Mechanism of Milademetan, an MDM2 Inhibitor, in Intimal Sarcoma with MDM2 Amplification: An Open-Label Phase Ib/II Study.
Koyama T, Shimizu T, Kojima Y, Sudo K, Okuma HS, Shimoi T, Ichikawa H, Kohsaka S, Sadachi R, Hirakawa A, Yoshida A, Ando RM, Ueno T, Yanagaki M, Matsui N, Nakamura K, Yamamoto N, Yonemori K. Koyama T, et al. Among authors: yanagaki m. Cancer Discov. 2023 Aug 4;13(8):1814-1825. doi: 10.1158/2159-8290.CD-23-0419. Cancer Discov. 2023. PMID: 37369013 Clinical Trial.
Superior mesenteric vein/portal vein contact in preoperative imaging indicates biological malignancy in anatomically resectable pancreatic cancer.
Shirai Y, Onda S, Tanji Y, Hamura R, Matsumoto M, Yanagaki M, Tsunematsu M, Taniai T, Haruki K, Furukawa K, Abe K, Sakamoto T, Gocho T, Uwagawa T, Ikegami T. Shirai Y, et al. Among authors: yanagaki m. Surg Oncol. 2023 Dec;51:101998. doi: 10.1016/j.suronc.2023.101998. Epub 2023 Sep 20. Surg Oncol. 2023. PMID: 37769516
High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer.
Mizuno S, Ikegami M, Koyama T, Sunami K, Ogata D, Kage H, Yanagaki M, Ikeuchi H, Ueno T, Tanikawa M, Oda K, Osuga Y, Mano H, Kohsaka S. Mizuno S, et al. Among authors: yanagaki m. Mol Cancer Ther. 2023 Feb 1;22(2):227-239. doi: 10.1158/1535-7163.MCT-22-0302. Mol Cancer Ther. 2023. PMID: 36442478 Free PMC article.
Inhibition of acid ceramidase elicits mitochondrial dysfunction and oxidative stress in pancreatic cancer cells.
Taniai T, Shirai Y, Shimada Y, Hamura R, Yanagaki M, Takada N, Horiuchi T, Haruki K, Furukawa K, Uwagawa T, Tsuboi K, Okamoto Y, Shimada S, Tanaka S, Ohashi T, Ikegami T. Taniai T, et al. Among authors: yanagaki m. Cancer Sci. 2021 Nov;112(11):4570-4579. doi: 10.1111/cas.15123. Epub 2021 Sep 13. Cancer Sci. 2021. PMID: 34459070 Free PMC article.
49 results