Yan X - Search Results

1

Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies.

Sun LL, Ellerman D, Mathieu M, Hristopoulos M, Chen X, Li Y, Yan X, Clark R, Reyes A, Stefanich E, Mai E, Young J, Johnson C, Huseni M, Wang X, Chen Y, Wang P, Wang H, Dybdal N, Chu YW, Chiorazzi N, Scheer JM, Junttila T, Totpal K, Dennis MS, Ebens AJ. Sun LL, et al. Among authors: yan x. Sci Transl Med. 2015 May 13;7(287):287ra70. doi: 10.1126/scitranslmed.aaa4802. Sci Transl Med. 2015. PMID: 25972002

2

B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia.

Yan XJ, Albesiano E, Zanesi N, Yancopoulos S, Sawyer A, Romano E, Petlickovski A, Efremov DG, Croce CM, Chiorazzi N. Yan XJ, et al. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11713-8. doi: 10.1073/pnas.0604564103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864779 Free PMC article.

3

Surface expression of Bcl-2 in chronic lymphocytic leukemia and other B-cell leukemias and lymphomas without a breakpoint t(14;18).

McCarthy BA, Boyle E, Wang XP, Guzowski D, Paul S, Catera R, Trott J, Yan XJ, Croce CM, Damle R, Yancopoulos S, Messmer BT, Lesser M, Allen SL, Rai KR, Chiorazzi N. McCarthy BA, et al. Mol Med. 2008 Sep-Oct;14(9-10):618-27. doi: 10.2119/2008.00061.McCarthy. Mol Med. 2008. PMID: 18633450 Free PMC article.

4

Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA.

Chu CC, Catera R, Hatzi K, Yan XJ, Zhang L, Wang XB, Fales HM, Allen SL, Kolitz JE, Rai KR, Chiorazzi N. Chu CC, et al. Blood. 2008 Dec 15;112(13):5122-9. doi: 10.1182/blood-2008-06-162024. Epub 2008 Sep 23. Blood. 2008. PMID: 18812466 Free PMC article.

5

Indole-3-carbinol improves survival in lupus-prone mice by inducing tandem B- and T-cell differentiation blockades.

Yan XJ, Qi M, Telusma G, Yancopoulos S, Madaio M, Satoh M, Reeves WH, Teichberg S, Kohn N, Auborn K, Chiorazzi N. Yan XJ, et al. Clin Immunol. 2009 Jun;131(3):481-94. doi: 10.1016/j.clim.2009.01.013. Epub 2009 Mar 10. Clin Immunol. 2009. PMID: 19278904

6

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease.

Bagnara D, Kaufman MS, Calissano C, Marsilio S, Patten PE, Simone R, Chum P, Yan XJ, Allen SL, Kolitz JE, Baskar S, Rader C, Mellstedt H, Rabbani H, Lee A, Gregersen PK, Rai KR, Chiorazzi N. Bagnara D, et al. Blood. 2011 May 19;117(20):5463-72. doi: 10.1182/blood-2010-12-324210. Epub 2011 Mar 8. Blood. 2011. PMID: 21385850 Free PMC article.

7

Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia.

Yan XJ, Dozmorov I, Li W, Yancopoulos S, Sison C, Centola M, Jain P, Allen SL, Kolitz JE, Rai KR, Chiorazzi N, Sherry B. Yan XJ, et al. Blood. 2011 Nov 10;118(19):5201-10. doi: 10.1182/blood-2011-03-342436. Epub 2011 Sep 12. Blood. 2011. PMID: 21911837 Free PMC article.

8

IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions.

Patten PE, Chu CC, Albesiano E, Damle RN, Yan XJ, Kim D, Zhang L, Magli AR, Barrientos J, Kolitz JE, Allen SL, Rai KR, Roa S, Mongini PK, MacCarthy T, Scharff MD, Chiorazzi N. Patten PE, et al. Blood. 2012 Dec 6;120(24):4802-11. doi: 10.1182/blood-2012-08-449744. Epub 2012 Oct 15. Blood. 2012. PMID: 23071276 Free PMC article.

9

Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: results from single cell network profiling studies.

Cesano A, Perbellini O, Evensen E, Chu CC, Cioffi F, Ptacek J, Damle RN, Chignola R, Cordeiro J, Yan XJ, Hawtin RE, Nichele I, Ware JR, Cavallini C, Lovato O, Zanotti R, Rai KR, Chiorazzi N, Pizzolo G, Scupoli MT. Cesano A, et al. Haematologica. 2013 Apr;98(4):626-34. doi: 10.3324/haematol.2012.071910. Epub 2012 Nov 9. Haematologica. 2013. PMID: 23144194 Free PMC article.

10

Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling.

Chen SS, Batliwalla F, Holodick NE, Yan XJ, Yancopoulos S, Croce CM, Rothstein TL, Chiorazzi N. Chen SS, et al. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1500-7. doi: 10.1073/pnas.1300616110. Epub 2013 Apr 2. Proc Natl Acad Sci U S A. 2013. PMID: 23550156 Free PMC article.

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