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Single-Cell Analysis Reveals Malignant Cells Reshape the Cellular Landscape and Foster an Immunosuppressive Microenvironment of Extranodal NK/T-Cell Lymphoma.
Li YQ, Luo CL, Jiang JX, He S, Liu Y, Yan WX, Xia Y, Cui Q, Huang Y, Lim JQ, Huang D, Hussein IN, Gao Y, Lin GW, Ling YH, Ma D, Zhang YT, Chan JY, Wei PP, Wang XX, Cheng CL, Xiong J, Zhao WL, Ong CK, Lim ST, Huang HQ, Peng RJ, Bei JX. Li YQ, et al. Among authors: yan wx. Adv Sci (Weinh). 2023 Dec;10(36):e2303913. doi: 10.1002/advs.202303913. Epub 2023 Nov 10. Adv Sci (Weinh). 2023. PMID: 37949673 Free PMC article.
The miniature CRISPR-Cas12m effector binds DNA to block transcription.
Wu WY, Mohanraju P, Liao C, Adiego-Pérez B, Creutzburg SCA, Makarova KS, Keessen K, Lindeboom TA, Khan TS, Prinsen S, Joosten R, Yan WX, Migur A, Laffeber C, Scott DA, Lebbink JHG, Koonin EV, Beisel CL, van der Oost J. Wu WY, et al. Among authors: yan wx. Mol Cell. 2022 Dec 1;82(23):4487-4502.e7. doi: 10.1016/j.molcel.2022.11.003. Epub 2022 Nov 24. Mol Cell. 2022. PMID: 36427491 Free article.
Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing.
McGaw C, Garrity AJ, Munoz GZ, Haswell JR, Sengupta S, Keston-Smith E, Hunnewell P, Ornstein A, Bose M, Wessells Q, Jakimo N, Yan P, Zhang H, Alfonse LE, Ziblat R, Carte JM, Lu WC, Cerchione D, Hilbert B, Sothiselvam S, Yan WX, Cheng DR, Scott DA, DiTommaso T, Chong S. McGaw C, et al. Among authors: yan wx. Nat Commun. 2022 May 20;13(1):2833. doi: 10.1038/s41467-022-30465-7. Nat Commun. 2022. PMID: 35595757 Free PMC article.
61 results