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Combinational study with network pharmacology, molecular docking and preliminary experiments on exploring common mechanisms underlying the effects of weijing decoction on various pulmonary diseases.
Li JX, Han ZX, Cheng X, Zhang FL, Zhang JY, Su ZJ, Li BP, Jiang ZR, Li RZ, Xie Y, Yan PY, Tang L, Yang JS. Li JX, et al. Among authors: yan py. Heliyon. 2023 Apr 20;9(5):e15631. doi: 10.1016/j.heliyon.2023.e15631. eCollection 2023 May. Heliyon. 2023. PMID: 37153415 Free PMC article.
Early lung cancer diagnostic biomarker discovery by machine learning methods.
Xie Y, Meng WY, Li RZ, Wang YW, Qian X, Chan C, Yu ZF, Fan XX, Pan HD, Xie C, Wu QB, Yan PY, Liu L, Tang YJ, Yao XJ, Wang MF, Leung EL. Xie Y, et al. Among authors: yan py. Transl Oncol. 2021 Jan;14(1):100907. doi: 10.1016/j.tranon.2020.100907. Epub 2020 Nov 17. Transl Oncol. 2021. PMID: 33217646 Free PMC article.
Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy.
Huang J, Liu D, Wang Y, Liu L, Li J, Yuan J, Jiang Z, Jiang Z, Hsiao WW, Liu H, Khan I, Xie Y, Wu J, Xie Y, Zhang Y, Fu Y, Liao J, Wang W, Lai H, Shi A, Cai J, Luo L, Li R, Yao X, Fan X, Wu Q, Liu Z, Yan P, Lu J, Yang M, Wang L, Cao Y, Wei H, Leung EL. Huang J, et al. Gut. 2022 Apr;71(4):734-745. doi: 10.1136/gutjnl-2020-321031. Epub 2021 May 18. Gut. 2022. PMID: 34006584 Free PMC article.
Metabolomics and integrated network pharmacology analysis reveal Tricin as the active anti-cancer component of Weijing decoction by suppression of PRKCA and sphingolipid signaling.
Li JX, Li RZ, Sun A, Zhou H, Neher E, Yang JS, Huang JM, Zhang YZ, Jiang ZB, Liang TL, Ma LR, Wang J, Wang XR, Fan XQ, Huang J, Xie Y, Liu L, Tang L, Leung EL, Yan PY. Li JX, et al. Among authors: yan py. Pharmacol Res. 2021 Sep;171:105574. doi: 10.1016/j.phrs.2021.105574. Epub 2021 Jul 25. Pharmacol Res. 2021. PMID: 34419228
A method establishment and comparison of in vivo lung cancer model development platforms for evaluation of tumour metabolism and pharmaceutical efficacy.
Liang TL, Li RZ, Mai CT, Guan XX, Li JX, Wang XR, Ma LR, Zhang FY, Wang J, He F, Pan HD, Zhou H, Yan PY, Fan XX, Wu QB, Neher E, Liu L, Xie Y, Leung EL, Yao XJ. Liang TL, et al. Among authors: yan py. Phytomedicine. 2022 Feb;96:153831. doi: 10.1016/j.phymed.2021.153831. Epub 2021 Nov 5. Phytomedicine. 2022. PMID: 34794861
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