Yan N - Search Results

1

Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C.

Chu TT, Tu X, Yang K, Wu J, Repa JJ, Yan N. Chu TT, et al. Among authors: yan n. Nature. 2021 Aug;596(7873):570-575. doi: 10.1038/s41586-021-03762-2. Epub 2021 Jul 21. Nature. 2021. PMID: 34290407 Free PMC article.

2

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes.

Hasan M, Koch J, Rakheja D, Pattnaik AK, Brugarolas J, Dozmorov I, Levine B, Wakeland EK, Lee-Kirsch MA, Yan N. Hasan M, et al. Among authors: yan n. Nat Immunol. 2013 Jan;14(1):61-71. doi: 10.1038/ni.2475. Epub 2012 Nov 18. Nat Immunol. 2013. PMID: 23160154 Free PMC article.

3

STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease.

Dobbs N, Burnaevskiy N, Chen D, Gonugunta VK, Alto NM, Yan N. Dobbs N, et al. Among authors: yan n. Cell Host Microbe. 2015 Aug 12;18(2):157-68. doi: 10.1016/j.chom.2015.07.001. Epub 2015 Jul 30. Cell Host Microbe. 2015. PMID: 26235147 Free PMC article.

4

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.

Hasan M, Gonugunta VK, Dobbs N, Ali A, Palchik G, Calvaruso MA, DeBerardinis RJ, Yan N. Hasan M, et al. Among authors: yan n. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):746-751. doi: 10.1073/pnas.1611113114. Epub 2017 Jan 9. Proc Natl Acad Sci U S A. 2017. PMID: 28069950 Free PMC article.

5

Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.

Kucej M, Fermaintt CS, Yang K, Irizarry-Caro RA, Yan N. Kucej M, et al. Among authors: yan n. Cell Rep. 2017 Mar 14;18(11):2600-2607. doi: 10.1016/j.celrep.2017.02.051. Cell Rep. 2017. PMID: 28297665 Free PMC article.

6

Methods of Assessing STING Activation and Trafficking.

Pokatayev V, Yan N. Pokatayev V, et al. Among authors: yan n. Methods Mol Biol. 2017;1656:167-174. doi: 10.1007/978-1-4939-7237-1_10. Methods Mol Biol. 2017. PMID: 28808969 Free PMC article.

7

STING-associated vasculopathy develops independently of IRF3 in mice.

Warner JD, Irizarry-Caro RA, Bennion BG, Ai TL, Smith AM, Miner CA, Sakai T, Gonugunta VK, Wu J, Platt DJ, Yan N, Miner JJ. Warner JD, et al. Among authors: yan n. J Exp Med. 2017 Nov 6;214(11):3279-3292. doi: 10.1084/jem.20171351. Epub 2017 Sep 26. J Exp Med. 2017. PMID: 28951494 Free PMC article.

8

Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response.

Gonugunta VK, Sakai T, Pokatayev V, Yang K, Wu J, Dobbs N, Yan N. Gonugunta VK, et al. Among authors: yan n. Cell Rep. 2017 Dec 12;21(11):3234-3242. doi: 10.1016/j.celrep.2017.11.061. Cell Rep. 2017. PMID: 29241549 Free PMC article.

9

N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1.

Yang K, Huang R, Fujihira H, Suzuki T, Yan N. Yang K, et al. Among authors: yan n. J Exp Med. 2018 Oct 1;215(10):2600-2616. doi: 10.1084/jem.20180783. Epub 2018 Aug 22. J Exp Med. 2018. PMID: 30135079 Free PMC article.

10

STIM1 moonlights as an anchor for STING.

Wu J, Yan N. Wu J, et al. Among authors: yan n. Nat Immunol. 2019 Feb;20(2):112-114. doi: 10.1038/s41590-018-0300-2. Nat Immunol. 2019. PMID: 30643261 No abstract available.

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