Yan N - Search Results

1

STING-associated vasculopathy develops independently of IRF3 in mice.

Warner JD, Irizarry-Caro RA, Bennion BG, Ai TL, Smith AM, Miner CA, Sakai T, Gonugunta VK, Wu J, Platt DJ, Yan N, Miner JJ. Warner JD, et al. Among authors: yan n. J Exp Med. 2017 Nov 6;214(11):3279-3292. doi: 10.1084/jem.20171351. Epub 2017 Sep 26. J Exp Med. 2017. PMID: 28951494 Free PMC article.

2

STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease.

Dobbs N, Burnaevskiy N, Chen D, Gonugunta VK, Alto NM, Yan N. Dobbs N, et al. Among authors: yan n. Cell Host Microbe. 2015 Aug 12;18(2):157-68. doi: 10.1016/j.chom.2015.07.001. Epub 2015 Jul 30. Cell Host Microbe. 2015. PMID: 26235147 Free PMC article.

3

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation.

Hasan M, Fermaintt CS, Gao N, Sakai T, Miyazaki T, Jiang S, Li QZ, Atkinson JP, Morse HC 3rd, Lehrman MA, Yan N. Hasan M, et al. Among authors: yan n. Immunity. 2015 Sep 15;43(3):463-74. doi: 10.1016/j.immuni.2015.07.022. Epub 2015 Aug 25. Immunity. 2015. PMID: 26320659 Free PMC article.

4

RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.

Pokatayev V, Hasin N, Chon H, Cerritelli SM, Sakhuja K, Ward JM, Morris HD, Yan N, Crouch RJ. Pokatayev V, et al. Among authors: yan n. J Exp Med. 2016 Mar 7;213(3):329-36. doi: 10.1084/jem.20151464. Epub 2016 Feb 15. J Exp Med. 2016. PMID: 26880576 Free PMC article.

5

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.

Hasan M, Gonugunta VK, Dobbs N, Ali A, Palchik G, Calvaruso MA, DeBerardinis RJ, Yan N. Hasan M, et al. Among authors: yan n. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):746-751. doi: 10.1073/pnas.1611113114. Epub 2017 Jan 9. Proc Natl Acad Sci U S A. 2017. PMID: 28069950 Free PMC article.

6

Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.

Kucej M, Fermaintt CS, Yang K, Irizarry-Caro RA, Yan N. Kucej M, et al. Among authors: yan n. Cell Rep. 2017 Mar 14;18(11):2600-2607. doi: 10.1016/j.celrep.2017.02.051. Cell Rep. 2017. PMID: 28297665 Free PMC article.

7

DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice.

Sakai T, Miyazaki T, Shin DM, Kim YS, Qi CF, Fariss R, Munasinghe J, Wang H, Kovalchuk AL, Kothari PH, Fermaintt CS, Atkinson JP, Perrino FW, Yan N, Morse HC 3rd. Sakai T, et al. Among authors: yan n. J Autoimmun. 2017 Jul;81:13-23. doi: 10.1016/j.jaut.2017.03.001. Epub 2017 Mar 18. J Autoimmun. 2017. PMID: 28325644 Free PMC article.

8

Immune Diseases Associated with TREX1 and STING Dysfunction.

Yan N. Yan N. J Interferon Cytokine Res. 2017 May;37(5):198-206. doi: 10.1089/jir.2016.0086. J Interferon Cytokine Res. 2017. PMID: 28475463 Free PMC article. Review.

9

Methods of Assessing STING Activation and Trafficking.

Pokatayev V, Yan N. Pokatayev V, et al. Among authors: yan n. Methods Mol Biol. 2017;1656:167-174. doi: 10.1007/978-1-4939-7237-1_10. Methods Mol Biol. 2017. PMID: 28808969 Free PMC article.

10

Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response.

Gonugunta VK, Sakai T, Pokatayev V, Yang K, Wu J, Dobbs N, Yan N. Gonugunta VK, et al. Among authors: yan n. Cell Rep. 2017 Dec 12;21(11):3234-3242. doi: 10.1016/j.celrep.2017.11.061. Cell Rep. 2017. PMID: 29241549 Free PMC article.

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