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Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis.
Liu M, Cao S, He L, Gao J, Arab JP, Cui H, Xuan W, Gao Y, Sehrawat TS, Hamdan FH, Ventura-Cots M, Argemi J, Pomerantz WCK, Johnsen SA, Lee JH, Gao F, Ordog T, Mathurin P, Revzin A, Bataller R, Yan H, Shah VH. Liu M, et al. Among authors: yan h. Nat Commun. 2021 Jul 27;12(1):4560. doi: 10.1038/s41467-021-24843-w. Nat Commun. 2021. PMID: 34315876 Free PMC article.
CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.
Karakashev S, Zhu H, Wu S, Yokoyama Y, Bitler BG, Park PH, Lee JH, Kossenkov AV, Gaonkar KS, Yan H, Drapkin R, Conejo-Garcia JR, Speicher DW, Ordog T, Zhang R. Karakashev S, et al. Among authors: yan h. Nat Commun. 2018 Feb 12;9(1):631. doi: 10.1038/s41467-018-03031-3. Nat Commun. 2018. PMID: 29434212 Free PMC article.
Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.
Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R. Lomberk G, et al. Among authors: yan h. Nat Commun. 2018 May 17;9(1):1978. doi: 10.1038/s41467-018-04383-6. Nat Commun. 2018. PMID: 29773832 Free PMC article.
Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma.
Luchtel RA, Zimmermann MT, Hu G, Dasari S, Jiang M, Oishi N, Jacobs HK, Zeng Y, Hundal T, Rech KL, Ketterling RP, Lee JH, Eckloff BW, Yan H, Gaonkar KS, Tian S, Ye Z, Kadin ME, Sidhu J, Jiang L, Voss J, Link BK, Syrbu SI, Facchetti F, Bennani NN, Slager SL, Ordog T, Kocher JP, Cerhan JR, Ansell SM, Feldman AL. Luchtel RA, et al. Among authors: yan h. Blood. 2019 Jun 27;133(26):2776-2789. doi: 10.1182/blood.2019000626. Epub 2019 May 17. Blood. 2019. PMID: 31101622 Free PMC article.
Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas.
Lenkiewicz E, Malasi S, Hogenson TL, Flores LF, Barham W, Phillips WJ, Roesler AS, Chambers KR, Rajbhandari N, Hayashi A, Antal CE, Downes M, Grandgenett PM, Hollingsworth MA, Cridebring D, Xiong Y, Lee JH, Ye Z, Yan H, Hernandez MC, Leiting JL, Evans RM, Ordog T, Truty MJ, Borad MJ, Reya T, Von Hoff DD, Fernandez-Zapico ME, Barrett MT. Lenkiewicz E, et al. Among authors: yan h. Cancer Res. 2020 Oct 15;80(20):4324-4334. doi: 10.1158/0008-5472.CAN-20-0078. Epub 2020 Sep 14. Cancer Res. 2020. PMID: 32928922 Free PMC article.
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation.
Jones DL, Meridew JA, Link PA, Ducharme MT, Lydon KL, Choi KM, Caporarello N, Tan Q, Diaz Espinosa AM, Xiong Y, Lee JH, Ye Z, Yan H, Ordog T, Ligresti G, Varelas X, Tschumperlin DJ. Jones DL, et al. Among authors: yan h. J Cell Biol. 2021 May 3;220(5):e202007152. doi: 10.1083/jcb.202007152. J Cell Biol. 2021. PMID: 33625469 Free PMC article.
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