Yan C - Search Results

1

Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation.

Jiang B, Zhao X, Chen W, Diao W, Ding M, Qin H, Li B, Cao W, Chen W, Fu Y, He K, Gao J, Chen M, Lin T, Deng Y, Yan C, Guo H. Jiang B, et al. Among authors: yan c. Nat Commun. 2022 Jul 16;13(1):4141. doi: 10.1038/s41467-022-31783-6. Nat Commun. 2022. PMID: 35842443 Free PMC article.

2

Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.

Zhang Y, Wu J, Fu Y, Yu R, Su H, Zheng Q, Wu H, Zhou S, Wang K, Zhao J, Shen S, Xu G, Wang L, Yan C, Zou X, Lv Y, Zhang S. Zhang Y, et al. Among authors: yan c. Oncogene. 2022 Jun;41(25):3394-3408. doi: 10.1038/s41388-022-02328-4. Epub 2022 May 12. Oncogene. 2022. PMID: 35551503

3

Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.

Zhang S, Fang W, Zhou S, Zhu D, Chen R, Gao X, Li Z, Fu Y, Zhang Y, Yang F, Zhao J, Wu H, Wang P, Shen Y, Shen S, Xu G, Wang L, Yan C, Zou X, Chen D, Lv Y. Zhang S, et al. Among authors: yan c. Nat Commun. 2023 Aug 23;14(1):5123. doi: 10.1038/s41467-023-40727-7. Nat Commun. 2023. PMID: 37612267 Free PMC article.

4

A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers.

Cheng R, Li F, Zhang M, Xia X, Wu J, Gao X, Zhou H, Zhang Z, Huang N, Yang X, Zhang Y, Shen S, Kang T, Liu Z, Xiao F, Yao H, Xu J, Yan C, Zhang N. Cheng R, et al. Among authors: yan c. Cell Res. 2023 Jan;33(1):30-45. doi: 10.1038/s41422-022-00726-7. Epub 2022 Oct 14. Cell Res. 2023. PMID: 36241718 Free PMC article.

5

Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.

Chen ZP, Wang S, Zhao X, Fang W, Wang Z, Ye H, Wang MJ, Ke L, Huang T, Lv P, Jiang X, Zhang Q, Li L, Xie ST, Zhu JN, Hang C, Chen D, Liu X, Yan C. Chen ZP, et al. Among authors: yan c. Nat Neurosci. 2023 Apr;26(4):542-554. doi: 10.1038/s41593-023-01288-6. Epub 2023 Mar 20. Nat Neurosci. 2023. PMID: 36941428

6

Discovery and characterization of small molecules that target the GTPase Ral.

Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, Schwartz MA, Jones DN, Ross D, Meroueh SO, Theodorescu D. Yan C, et al. Nature. 2014 Nov 20;515(7527):443-7. doi: 10.1038/nature13713. Epub 2014 Sep 14. Nature. 2014. PMID: 25219851 Free PMC article.

7

Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.

Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C. Huang T, et al. Among authors: yan c. Autophagy. 2021 Nov;17(11):3592-3606. doi: 10.1080/15548627.2021.1885203. Epub 2021 Feb 25. Autophagy. 2021. PMID: 33629929 Free PMC article.

8

In vivo self-assembled small RNAs as a new generation of RNAi therapeutics.

Fu Z, Zhang X, Zhou X, Ur-Rehman U, Yu M, Liang H, Guo H, Guo X, Kong Y, Su Y, Ye Y, Hu X, Cheng W, Wu J, Wang Y, Gu Y, Lu SF, Wu D, Zen K, Li J, Yan C, Zhang CY, Chen X. Fu Z, et al. Among authors: yan c. Cell Res. 2021 Jun;31(6):631-648. doi: 10.1038/s41422-021-00491-z. Epub 2021 Mar 29. Cell Res. 2021. PMID: 33782530 Free PMC article.

9

Design, synthesis, and evaluation of 4(1H)-quinolinone and urea derivatives as KRAS^G12C inhibitors with potent antitumor activity against KRAS-mutant non-small cell lung cancer.

Cheng R, Lv X, Bu H, Xu Q, Wu J, Xie K, Tang J, Wang L, Zhuang J, Zhang Y, Zhang Y, Yan C, Lai Y. Cheng R, et al. Among authors: yan c. Eur J Med Chem. 2022 Dec 15;244:114808. doi: 10.1016/j.ejmech.2022.114808. Epub 2022 Oct 1. Eur J Med Chem. 2022. PMID: 36228411

10

RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.

Yan C, Theodorescu D. Yan C, et al. Pharmacol Rev. 2018 Jan;70(1):1-11. doi: 10.1124/pr.117.014415. Pharmacol Rev. 2018. PMID: 29196555 Free PMC article. Review.

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