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Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system.
Yamatsugu K, Katoh H, Yamashita T, Takahashi K, Aki S, Tatsumi T, Kaneko Y, Kawamura T, Miura M, Ishii M, Ohkubo K, Osawa T, Kodama T, Ishikawa S, Kanai M, Sugiyama A. Yamatsugu K, et al. Among authors: yamashita t. Protein Expr Purif. 2022 Apr;192:106043. doi: 10.1016/j.pep.2021.106043. Epub 2021 Dec 30. Protein Expr Purif. 2022. PMID: 34973460 Free article.
Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses.
Nakayama T, Mizohata E, Yamashita T, Nagatoishi S, Nakakido M, Iwanari H, Mochizuki Y, Kado Y, Yokota Y, Satoh R, Tsumoto K, Fujitani H, Kodama T, Hamakubo T, Inoue T. Nakayama T, et al. Among authors: yamashita t. Protein Sci. 2015 Mar;24(3):328-40. doi: 10.1002/pro.2619. Epub 2015 Jan 13. Protein Sci. 2015. PMID: 25492858 Free PMC article.
Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Yamashita T, Mizohata E, Nagatoishi S, Watanabe T, Nakakido M, Iwanari H, Mochizuki Y, Nakayama T, Kado Y, Yokota Y, Matsumura H, Kawamura T, Kodama T, Hamakubo T, Inoue T, Fujitani H, Tsumoto K. Yamashita T, et al. Structure. 2019 Mar 5;27(3):519-527.e5. doi: 10.1016/j.str.2018.11.002. Epub 2018 Dec 27. Structure. 2019. PMID: 30595454 Free article.
Cupid and Psyche system for the diagnosis and treatment of advanced cancer.
Sugiyama A, Kawamura T, Tanaka T, Doi H, Yamashita T, Shinoda K, Fujitani H, Yamatsugu K, Shimizu Y, Tatsumi T, Takahashi K, Kanai M, Mizohata E, Kawato T, Doi T, Inoue T, Kodama T. Sugiyama A, et al. Among authors: yamashita t. Proc Jpn Acad Ser B Phys Biol Sci. 2019;95(10):602-611. doi: 10.2183/pjab.95.041. Proc Jpn Acad Ser B Phys Biol Sci. 2019. PMID: 31827018 Free PMC article. Review.
Pathological complete remission of relapsed tumor by photo-activating antibody-mimetic drug conjugate treatment.
Kaneko Y, Yamatsugu K, Yamashita T, Takahashi K, Tanaka T, Aki S, Tatsumi T, Kawamura T, Miura M, Ishii M, Ohkubo K, Osawa T, Kodama T, Ishikawa S, Tsukagoshi M, Chansler M, Sugiyama A, Kanai M, Katoh H. Kaneko Y, et al. Among authors: yamashita t. Cancer Sci. 2022 Dec;113(12):4350-4362. doi: 10.1111/cas.15565. Epub 2022 Sep 19. Cancer Sci. 2022. PMID: 36121618 Free PMC article.
Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin.
Sakata J, Tatsumi T, Sugiyama A, Shimizu A, Inagaki Y, Katoh H, Yamashita T, Takahashi K, Aki S, Kaneko Y, Kawamura T, Miura M, Ishii M, Osawa T, Tanaka T, Ishikawa S, Tsukagoshi M, Chansler M, Kodama T, Kanai M, Tokuyama H, Yamatsugu K. Sakata J, et al. Among authors: yamashita t. Protein Expr Purif. 2024 Feb;214:106375. doi: 10.1016/j.pep.2023.106375. Epub 2023 Oct 4. Protein Expr Purif. 2024. PMID: 37797818 Free article.
6,777 results