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Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Anzai A, Shimoda M, Endo J, Kohno T, Katsumata Y, Matsuhashi T, Yamamoto T, Ito K, Yan X, Shirakawa K, Shimizu-Hirota R, Yamada Y, Ueha S, Shinmura K, Okada Y, Fukuda K, Sano M. Anzai A, et al. Among authors: yamamoto t. Circ Res. 2015 Feb 13;116(4):612-23. doi: 10.1161/CIRCRESAHA.116.304918. Epub 2015 Jan 6. Circ Res. 2015. PMID: 25563839
Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.
Yamamoto T, Tamaki K, Shirakawa K, Ito K, Yan X, Katsumata Y, Anzai A, Matsuhashi T, Endo J, Inaba T, Tsubota K, Sano M, Fukuda K, Shinmura K. Yamamoto T, et al. Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H1003-14. doi: 10.1152/ajpheart.00676.2015. Epub 2016 Feb 12. Am J Physiol Heart Circ Physiol. 2016. PMID: 26873964 Free article.
We previously found the essential roles of endothelial nitric oxide synthase in the development of CR-induced cardioprotection and Sirt1 activation during CR (Shinmura K, Tamaki K, Ito K, Yan X, Yamamoto T, Katsumata Y, Matsuhashi T, Sano M, Fukuda K, Suemats …
We previously found the essential roles of endothelial nitric oxide synthase in the development of CR-induced cardioprotection and Sirt1 act …
Negative legacy of obesity.
Shirakawa K, Endo J, Katsumata Y, Yamamoto T, Kataoka M, Isobe S, Yoshida N, Fukuda K, Sano M. Shirakawa K, et al. Among authors: yamamoto t. PLoS One. 2017 Oct 26;12(10):e0186303. doi: 10.1371/journal.pone.0186303. eCollection 2017. PLoS One. 2017. PMID: 29073165 Free PMC article.
Decrease in membrane phospholipids unsaturation correlates with myocardial diastolic dysfunction.
Yamamoto T, Endo J, Kataoka M, Matsuhashi T, Katsumata Y, Shirakawa K, Yoshida N, Isobe S, Moriyama H, Goto S, Yamashita K, Nakanishi H, Shimanaka Y, Kono N, Shinmura K, Arai H, Fukuda K, Sano M. Yamamoto T, et al. PLoS One. 2018 Dec 11;13(12):e0208396. doi: 10.1371/journal.pone.0208396. eCollection 2018. PLoS One. 2018. PMID: 30533011 Free PMC article.
Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension.
Isobe S, Kataoka M, Endo J, Moriyama H, Okazaki S, Tsuchihashi K, Katsumata Y, Yamamoto T, Shirakawa K, Yoshida N, Shimoda M, Chiba T, Masuko T, Hakamata Y, Kobayashi E, Saya H, Fukuda K, Sano M. Isobe S, et al. Among authors: yamamoto t. Am J Respir Cell Mol Biol. 2019 Sep;61(3):367-379. doi: 10.1165/rcmb.2018-0231OC. Am J Respir Cell Mol Biol. 2019. PMID: 30897333
Pressure overload inhibits glucocorticoid receptor transcriptional activity in cardiomyocytes and promotes pathological cardiac hypertrophy.
Matsuhashi T, Endo J, Katsumata Y, Yamamoto T, Shimizu N, Yoshikawa N, Kataoka M, Isobe S, Moriyama H, Goto S, Fukuda K, Tanaka H, Sano M. Matsuhashi T, et al. Among authors: yamamoto t. J Mol Cell Cardiol. 2019 May;130:122-130. doi: 10.1016/j.yjmcc.2019.03.019. Epub 2019 Apr 1. J Mol Cell Cardiol. 2019. PMID: 30946837
Sirt1 counteracts decrease in membrane phospholipid unsaturation and diastolic dysfunction during saturated fatty acid overload.
Yamamoto T, Endo J, Kataoka M, Matsuhashi T, Katsumata Y, Shirakawa K, Yoshida N, Isobe S, Moriyama H, Goto S, Yamashita K, Ohto-Nakanishi T, Nakanishi H, Shimanaka Y, Kono N, Shinmura K, Arai H, Fukuda K, Sano M. Yamamoto T, et al. J Mol Cell Cardiol. 2019 Aug;133:1-11. doi: 10.1016/j.yjmcc.2019.05.019. Epub 2019 May 27. J Mol Cell Cardiol. 2019. PMID: 31145942
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