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Page 1
Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.
Nakagawa Y, Satoh A, Yabe S, Furusawa M, Tokushige N, Tezuka H, Mikami M, Iwata W, Shingyouchi A, Matsuzaka T, Kiwata S, Fujimoto Y, Shimizu H, Danno H, Yamamoto T, Ishii K, Karasawa T, Takeuchi Y, Iwasaki H, Shimada M, Kawakami Y, Urayama O, Sone H, Takekoshi K, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Suzuki H, Yamada N, Shimano H. Nakagawa Y, et al. Among authors: yamada n. Endocrinology. 2014 Dec;155(12):4706-19. doi: 10.1210/en.2014-1113. Epub 2014 Sep 18. Endocrinology. 2014. PMID: 25233440
Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status.
Sone H, Shimano H, Sakakura Y, Inoue N, Amemiya-Kudo M, Yahagi N, Osawa M, Suzuki H, Yokoo T, Takahashi A, Iida K, Toyoshima H, Iwama A, Yamada N. Sone H, et al. Among authors: yamada n. Am J Physiol Endocrinol Metab. 2002 Jan;282(1):E222-30. doi: 10.1152/ajpendo.00189.2001. Am J Physiol Endocrinol Metab. 2002. PMID: 11739104 Free article.
The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.
Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H. Danno H, et al. Among authors: yamada n. Biochem Biophys Res Commun. 2010 Jan 8;391(2):1222-7. doi: 10.1016/j.bbrc.2009.12.046. Epub 2009 Dec 16. Biochem Biophys Res Commun. 2010. PMID: 20006574
TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice.
Iwasaki H, Naka A, Iida KT, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H. Iwasaki H, et al. Among authors: yamada n. Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E896-902. doi: 10.1152/ajpendo.00204.2011. Epub 2012 Jan 31. Am J Physiol Endocrinol Metab. 2012. PMID: 22297304 Free article.
TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis.
Fujimoto Y, Nakagawa Y, Satoh A, Okuda K, Shingyouchi A, Naka A, Matsuzaka T, Iwasaki H, Kobayashi K, Yahagi N, Shimada M, Yatoh S, Suzuki H, Yogosawa S, Izumi T, Sone H, Urayama O, Yamada N, Shimano H. Fujimoto Y, et al. Among authors: yamada n. Endocrinology. 2013 Oct;154(10):3577-88. doi: 10.1210/en.2013-1203. Epub 2013 Jul 24. Endocrinology. 2013. PMID: 23885019
Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.
Nakagawa Y, Oikawa F, Mizuno S, Ohno H, Yagishita Y, Satoh A, Osaki Y, Takei K, Kikuchi T, Han SI, Matsuzaka T, Iwasaki H, Kobayashi K, Yatoh S, Yahagi N, Isaka M, Suzuki H, Sone H, Takahashi S, Yamada N, Shimano H. Nakagawa Y, et al. Among authors: yamada n. Sci Rep. 2016 Jun 13;6:27857. doi: 10.1038/srep27857. Sci Rep. 2016. PMID: 27291420 Free PMC article.
CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.
Nakagawa Y, Satoh A, Tezuka H, Han SI, Takei K, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Iwasaki Y, Sone H, Matsuzaka T, Yamada N, Shimano H. Nakagawa Y, et al. Among authors: yamada n. Sci Rep. 2016 Dec 16;6:39182. doi: 10.1038/srep39182. Sci Rep. 2016. PMID: 27982131 Free PMC article.
Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.
Ohno H, Matsuzaka T, Tang N, Sharma R, Motomura K, Shimura T, Satoh A, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Nakagawa Y, Sone H, Yahagi N, Yamada N, Higami Y, Shimano H. Ohno H, et al. Among authors: yamada n. Endocrinology. 2018 Jun 1;159(6):2308-2323. doi: 10.1210/en.2017-03179. Endocrinology. 2018. PMID: 29668871
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.
Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N. Ide T, et al. Among authors: yamada n. Mol Endocrinol. 2003 Jul;17(7):1255-67. doi: 10.1210/me.2002-0191. Epub 2003 May 1. Mol Endocrinol. 2003. PMID: 12730332
Taken together with data from the accompanying paper (Yoshikawa, T., T. Ide, H. Shimano, N. Yahagi, M. Amemiya-Kudo, T. Matsuzaka, S. Yatoh, T. Kitamine, H. ...Takahashi, A. H. Hasty, R. Sato, H. Sone, J. Osuga, S. Ishibashi, and N. Yamada, Endocrinology 144: …
Taken together with data from the accompanying paper (Yoshikawa, T., T. Ide, H. Shimano, N. Yahagi, M. Amemiya-Kudo, T. Matsuzaka, S. …
SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.
Yamamoto T, Shimano H, Nakagawa Y, Ide T, Yahagi N, Matsuzaka T, Nakakuki M, Takahashi A, Suzuki H, Sone H, Toyoshima H, Sato R, Yamada N. Yamamoto T, et al. Among authors: yamada n. J Biol Chem. 2004 Mar 26;279(13):12027-35. doi: 10.1074/jbc.M310333200. Epub 2004 Jan 13. J Biol Chem. 2004. PMID: 14722127 Free article.
3,097 results