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MRP1-Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia-Reperfusion.
Ichihara G, Katsumata Y, Sugiura Y, Matsuoka Y, Maeda R, Endo J, Anzai A, Shirakawa K, Moriyama H, Kitakata H, Hiraide T, Goto S, Ko S, Iwasawa Y, Sugai K, Daigo K, Goto S, Sato K, Yamada KI, Suematsu M, Ieda M, Sano M. Ichihara G, et al. Among authors: yamada ki. Circ Res. 2023 Oct 27;133(10):861-876. doi: 10.1161/CIRCRESAHA.123.323517. Epub 2023 Oct 11. Circ Res. 2023. PMID: 37818671
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury.
Miyamoto HD, Ikeda M, Ide T, Tadokoro T, Furusawa S, Abe K, Ishimaru K, Enzan N, Sada M, Yamamoto T, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H. Miyamoto HD, et al. Among authors: yamada ki. JACC Basic Transl Sci. 2022 Jul 27;7(8):800-819. doi: 10.1016/j.jacbts.2022.03.012. eCollection 2022 Aug. JACC Basic Transl Sci. 2022. PMID: 36061338 Free PMC article.
Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis.
Abe K, Ikeda M, Ide T, Tadokoro T, Miyamoto HD, Furusawa S, Tsutsui Y, Miyake R, Ishimaru K, Watanabe M, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H. Abe K, et al. Among authors: yamada ki. Sci Signal. 2022 Nov;15(758):eabn8017. doi: 10.1126/scisignal.abn8017. Epub 2022 Nov 1. Sci Signal. 2022. PMID: 36318618
143 results