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The Keap1-Nrf2 system prevents onset of diabetes mellitus.
Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M. Uruno A, et al. Among authors: yagishita y. Mol Cell Biol. 2013 Aug;33(15):2996-3010. doi: 10.1128/MCB.00225-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716596 Free PMC article.
Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice.
Chartoumpekis DV, Palliyaguru DL, Wakabayashi N, Fazzari M, Khoo NKH, Schopfer FJ, Sipula I, Yagishita Y, Michalopoulos GK, O'Doherty RM, Kensler TW. Chartoumpekis DV, et al. Among authors: yagishita y. Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E180-E195. doi: 10.1152/ajpendo.00311.2017. Epub 2018 Feb 27. Am J Physiol Endocrinol Metab. 2018. PMID: 29486138 Free PMC article.
Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.
Chartoumpekis DV, Yagishita Y, Fazzari M, Palliyaguru DL, Rao UN, Zaravinos A, Khoo NK, Schopfer FJ, Weiss KR, Michalopoulos GK, Sipula I, O'Doherty RM, Kensler TW, Wakabayashi N. Chartoumpekis DV, et al. Among authors: yagishita y. JCI Insight. 2018 Mar 8;3(5):e97735. doi: 10.1172/jci.insight.97735. JCI Insight. 2018. PMID: 29515034 Free PMC article.
Current Landscape of NRF2 Biomarkers in Clinical Trials.
Yagishita Y, Gatbonton-Schwager TN, McCallum ML, Kensler TW. Yagishita Y, et al. Antioxidants (Basel). 2020 Aug 7;9(8):716. doi: 10.3390/antiox9080716. Antioxidants (Basel). 2020. PMID: 32784785 Free PMC article. Review.
NRF2 and the Moirai: Life and Death Decisions on Cell Fates.
Yagishita Y, Chartoumpekis DV, Kensler TW, Wakabayashi N. Yagishita Y, et al. Antioxid Redox Signal. 2023 Mar;38(7-9):684-708. doi: 10.1089/ars.2022.0200. Epub 2023 Feb 22. Antioxid Redox Signal. 2023. PMID: 36509429 Free PMC article. Review.
56 results