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Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.
Qiao L, Hamamichi S, Caldwell KA, Caldwell GA, Yacoubian TA, Wilson S, Xie ZL, Speake LD, Parks R, Crabtree D, Liang Q, Crimmins S, Schneider L, Uchiyama Y, Iwatsubo T, Zhou Y, Peng L, Lu Y, Standaert DG, Walls KC, Shacka JJ, Roth KA, Zhang J. Qiao L, et al. Among authors: yacoubian ta. Mol Brain. 2008 Nov 21;1:17. doi: 10.1186/1756-6606-1-17. Mol Brain. 2008. PMID: 19021916 Free PMC article.
α-Synuclein overexpression represses 14-3-3θ transcription.
Ding H, Fineberg NS, Gray M, Yacoubian TA. Ding H, et al. Among authors: yacoubian ta. J Mol Neurosci. 2013 Nov;51(3):1000-9. doi: 10.1007/s12031-013-0086-5. Epub 2013 Aug 4. J Mol Neurosci. 2013. PMID: 23912650 Free PMC article.
14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein.
Wang B, Underwood R, Kamath A, Britain C, McFerrin MB, McLean PJ, Volpicelli-Daley LA, Whitaker RH, Placzek WJ, Becker K, Ma J, Yacoubian TA. Wang B, et al. Among authors: yacoubian ta. J Neurosci. 2018 Sep 19;38(38):8211-8232. doi: 10.1523/JNEUROSCI.1134-18.2018. Epub 2018 Aug 9. J Neurosci. 2018. PMID: 30093536 Free PMC article.
44 results