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Boosting Mouse Defense against Lethal Toxoplasma gondii Infection with Full-Length and Soluble SAG1 Recombinant Protein.
Li X, Yuan W, He T, Guo R, Du X, He Y, Li X, El-Ashram S, Al-Olayan EM, Yang N, Sang X. Li X, et al. Vaccines (Basel). 2023 Nov 2;11(11):1678. doi: 10.3390/vaccines11111678. Vaccines (Basel). 2023. PMID: 38006011 Free PMC article.
Toxoplasmosis is a major worldwide protozoan zoonosis. The surface antigen 1 (SAG1) of Toxoplasma gondii (T. gondii) has always been recognized as an ideal vaccine candidate antigen. ...The levels of Th1-type cytokines (IFN-gamma, IL-12p70, IL-2, and TNF-alpha) and Th2-typ …
Toxoplasmosis is a major worldwide protozoan zoonosis. The surface antigen 1 (SAG1) of Toxoplasma gondii (T. gondii) has always been …
Co-Immunization with DNA Vaccines Expressing SABP1 and SAG1 Proteins Effectively Enhanced Mice Resistance to Toxoplasma gondii Acute Infection.
Sang X, Li X, Chen R, Feng Y, He T, Zhang X, El-Ashram S, Al-Olayan E, Yang N. Sang X, et al. Vaccines (Basel). 2023 Jul 2;11(7):1190. doi: 10.3390/vaccines11071190. Vaccines (Basel). 2023. PMID: 37515006 Free PMC article.
The combined DNA vaccine significantly increased the immunized mouse survival compared to the control group, with an average death time extended by 4.33 0.6 days (p < 0.0001). ...
The combined DNA vaccine significantly increased the immunized mouse survival compared to the control group, with an average death ti …