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Poly-2-methyl-2-oxazoline-modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration.
Zakharchenko A, Xue Y, Keeney S, Rock CA, Alferiev IS, Stachelek SJ, Takano H, Thomas T, Nagaswami C, Krieger AM, Chorny M, Ferrari G, Levy RJ. Zakharchenko A, et al. Among authors: xue y. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120694119. doi: 10.1073/pnas.2120694119. Proc Natl Acad Sci U S A. 2022. PMID: 35131859 Free PMC article.
Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves.
Frasca A, Xue Y, Kossar AP, Keeney S, Rock C, Zakharchenko A, Streeter M, Gorman RC, Grau JB, George I, Bavaria JE, Krieger A, Spiegel DA, Levy RJ, Ferrari G. Frasca A, et al. Among authors: xue y. JACC Basic Transl Sci. 2020 Aug 5;5(8):755-766. doi: 10.1016/j.jacbts.2020.06.008. eCollection 2020 Aug. JACC Basic Transl Sci. 2020. PMID: 32875167 Free PMC article.
Noncalcific Mechanisms of Bioprosthetic Structural Valve Degeneration.
Marro M, Kossar AP, Xue Y, Frasca A, Levy RJ, Ferrari G. Marro M, et al. Among authors: xue y. J Am Heart Assoc. 2021 Feb 2;10(3):e018921. doi: 10.1161/JAHA.120.018921. Epub 2021 Jan 26. J Am Heart Assoc. 2021. PMID: 33494616 Free PMC article. Review.
Altered Responsiveness to TGFβ and BMP and Increased CD45+ Cell Presence in Mitral Valves Are Unique Features of Ischemic Mitral Regurgitation.
Castillero E, Howsmon DP, Rego BV, Keeney SJ, Driesbaugh KH, Kawashima T, Xue (薛应騛) Y, Camillo C, George I, Gorman RC, Gorman JH 3rd, Sacks MS, Levy RJ, Ferrari G. Castillero E, et al. Among authors: xue y. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):2049-2062. doi: 10.1161/ATVBAHA.121.316111. Epub 2021 Apr 8. Arterioscler Thromb Vasc Biol. 2021. PMID: 33827255 Free PMC article.
Age-related enhanced degeneration of bioprosthetic valves due to leaflet calcification, tissue crosslinking, and structural changes.
Xue Y, Kossar AP, Abramov A, Frasca A, Sun M, Zyablitskaya M, Paik D, Kalfa D, Della Barbera M, Thiene G, Kozaki S, Kawashima T, Gorman JH, Gorman RC, Gillespie MJ, Carreon CK, Sanders SP, Levy RJ, Ferrari G. Xue Y, et al. Cardiovasc Res. 2023 Mar 17;119(1):302-315. doi: 10.1093/cvr/cvac002. Cardiovasc Res. 2023. PMID: 35020813 Free PMC article.
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